"Nuclear Matrix" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The residual framework structure of the CELL NUCLEUS that maintains many of the overall architectural features of the cell nucleus including the nuclear lamina with NUCLEAR PORE complex structures, residual CELL NUCLEOLI and an extensive fibrogranular structure in the nuclear interior. (Advan. Enzyme Regul. 2002; 42:39-52)
| Descriptor ID |
D015530
|
| MeSH Number(s) |
A11.284.430.106.279.345.700
|
| Concept/Terms |
Nuclear Matrix- Nuclear Matrix
- Matrices, Nuclear
- Matrix, Nuclear
- Nuclear Matrices
- Nucleoskeleton
- Nucleoskeletons
- Nuclear Scaffold
- Nuclear Scaffolds
- Scaffold, Nuclear
- Scaffolds, Nuclear
|
Below are MeSH descriptors whose meaning is more general than "Nuclear Matrix".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Matrix".
This graph shows the total number of publications written about "Nuclear Matrix" by people in this website by year, and whether "Nuclear Matrix" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 2000 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Matrix" by people in Profiles.
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Merbarone induces activation of caspase-activated DNase and excision of chromosomal DNA loops from the nuclear matrix. Mol Pharmacol. 2006 Apr; 69(4):1477-85.
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Phosphorylation of AML1/RUNX1 regulates its degradation and nuclear matrix association. Mol Cancer Res. 2005 Jul; 3(7):391-401.
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Topoisomerase II cleavable complex formation within DNA loop domains. Biochem Pharmacol. 2000 Jul 01; 60(1):101-9.
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The nuclear matrix as a site of anticancer drug action. Int Rev Cytol. 1995; 162A:539-76.
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DNA topoisomerase II isozymes involved in anticancer drug action and resistance. Adv Enzyme Regul. 1995; 35:265-81.