"Tacrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
| Descriptor ID |
D013619
|
| MeSH Number(s) |
D03.633.300.046.250.900
|
| Concept/Terms |
Tacrine- Tacrine
- 9-Amino-1,2,3,4-Tetrahydroacridine
- 1,2,3,4-Tetrahydro-9-acridinamine
- Tetrahydroaminoacridine
- 1,2,3,4-Tetrahydroaminoacridine
|
Below are MeSH descriptors whose meaning is more general than "Tacrine".
Below are MeSH descriptors whose meaning is more specific than "Tacrine".
This graph shows the total number of publications written about "Tacrine" by people in this website by year, and whether "Tacrine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tacrine" by people in Profiles.
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The secretion of amyloid beta-peptides is inhibited in the tacrine-treated human neuroblastoma cells. Brain Res Mol Brain Res. 1998 Nov 20; 62(2):131-40.
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The effect of tacrine and leupeptin on the secretion of the beta-amyloid precursor protein in HeLa cells. Life Sci. 1997; 61(20):1985-92.