Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
"Large-Conductance Calcium-Activated Potassium Channel alpha Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The pore-forming subunits of large-conductance calcium-activated potassium channels. They form tetramers in CELL MEMBRANES.
Descriptor ID |
D051037
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MeSH Number(s) |
D12.776.157.530.400.600.150.500.500 D12.776.543.550.450.750.150.500.500 D12.776.543.585.400.750.150.500.249
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Concept/Terms |
Large-Conductance Calcium-Activated Potassium Channel alpha Subunits- Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
- Large Conductance Calcium Activated Potassium Channel alpha Subunits
- Large-Conductance Calcium-Activated Potassium Channels, alpha Subunit
- Large Conductance Calcium Activated Potassium Channels, alpha Subunit
- MaxiK Channel alpha Subunit
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Below are MeSH descriptors whose meaning is more general than "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits".
Below are MeSH descriptors whose meaning is more specific than "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits".
This graph shows the total number of publications written about "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits" by people in this website by year, and whether "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Large-Conductance Calcium-Activated Potassium Channel alpha Subunits" by people in Profiles.
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Evaluating the safety and potential activity of URO-902 (hMaxi-K) gene transfer by intravesical instillation or direct injection into the bladder wall in female participants with idiopathic (non-neurogenic) overactive bladder syndrome and detrusor overactivity from two double-blind, imbalanced, placebo-controlled randomized phase 1 trials. Neurourol Urodyn. 2020 02; 39(2):744-753.
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Functional link between muscarinic receptors and large-conductance Ca2+ -activated K+ channels in freshly isolated human detrusor smooth muscle cells. Pflugers Arch. 2015 Apr; 467(4):665-75.
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Neurogenic detrusor overactivity is associated with decreased expression and function of the large conductance voltage- and Ca(2+)-activated K(+) channels. PLoS One. 2013; 8(7):e68052.
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Constitutively active phosphodiesterase activity regulates urinary bladder smooth muscle function: critical role of KCa1.1 channel. Am J Physiol Renal Physiol. 2012 Nov 01; 303(9):F1300-6.
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A voltage- and Ca2+-dependent big conductance K channel in cochlear spiral ligament fibrocytes. Pflugers Arch. 2003 Mar; 445(6):683-92.