"Conotoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Descriptor ID |
D020916
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MeSH Number(s) |
D20.888.590.162 D23.946.580.590.162 D23.946.833.590.162
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Conotoxins".
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Year | Major Topic | Minor Topic | Total |
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2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Conotoxins" by people in Profiles.
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Perineuronal nets labeled by monoclonal antibody VC1.1 ensheath interneurons expressing parvalbumin and calbindin in the rat amygdala. Brain Struct Funct. 2018 Apr; 223(3):1133-1148.