Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
"Precursor B-Cell Lymphoblastic Leukemia-Lymphoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A leukemia/lymphoma found predominately in children and adolescents and characterized by a high number of lymphoblasts and solid tumor lesions. Frequent sites involve LYMPH NODES, skin, and bones. It most commonly presents as leukemia.
| Descriptor ID |
D015452
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| MeSH Number(s) |
C04.557.337.428.600.600 C15.604.515.560.600.600 C20.683.515.528.600.600
|
| Concept/Terms |
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
- Precursor B Cell Lymphoblastic Leukemia Lymphoma
- Pre B-ALL
- Pre-B ALL
- Pre B ALL
- Precursor B-Cell Lymphoblastic Leukemia
- Precursor B Cell Lymphoblastic Leukemia
- Precursor B-Cell Lymphoblastic Lymphoma
- Precursor B Cell Lymphoblastic Lymphoma
- Leukemia, Pre-B-Cell
- Leukemia, Pre B Cell
- Leukemias, Pre-B-Cell
- Pre-B-Cell Leukemias
- Pre-B-Cell Leukemia
- Pre B Cell Leukemia
|
Below are MeSH descriptors whose meaning is more general than "Precursor B-Cell Lymphoblastic Leukemia-Lymphoma".
Below are MeSH descriptors whose meaning is more specific than "Precursor B-Cell Lymphoblastic Leukemia-Lymphoma".
This graph shows the total number of publications written about "Precursor B-Cell Lymphoblastic Leukemia-Lymphoma" by people in this website by year, and whether "Precursor B-Cell Lymphoblastic Leukemia-Lymphoma" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "Precursor B-Cell Lymphoblastic Leukemia-Lymphoma" by people in Profiles.
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TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Nat Commun. 2021 09 09; 12(1):5337.
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Favorable Trisomies and ETV6-RUNX1 Predict Cure in Low-Risk B-Cell Acute Lymphoblastic Leukemia: Results From Children's Oncology Group Trial AALL0331. J Clin Oncol. 2021 05 10; 39(14):1540-1552.
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Increased Incidence of IKZF1 deletions and IGH-CRLF2 translocations in B-ALL of Hispanic/Latino children-a novel health disparity. Leukemia. 2021 08; 35(8):2399-2402.
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The Current Genomic and Molecular Landscape of Philadelphia-like Acute Lymphoblastic Leukemia. Int J Mol Sci. 2020 Mar 22; 21(6).
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Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia. J Biol Chem. 2016 Feb 19; 291(8):4004-18.
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A novel xenograft model to study the role of TSLP-induced CRLF2 signals in normal and malignant human B lymphopoiesis. Haematologica. 2016 Apr; 101(4):417-26.
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Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia. Blood. 2015 Oct 08; 126(15):1813-22.
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Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy. Mol Cancer. 2007 Jul 10; 6:46.
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CD19 negative precursor B acute lymphoblastic leukemia presenting with hypercalcemia. Pediatr Blood Cancer. 2004 Jul; 43(1):66-9.
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Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis. J Cell Biol. 1999 Apr 05; 145(1):99-108.