"Immunotoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.
| Descriptor ID |
D000922
|
| MeSH Number(s) |
D12.776.124.790.651.114.580.450 D12.776.377.715.548.114.580.450 D27.888.569.271
|
| Concept/Terms |
Immunotoxins- Immunotoxins
- Cytotoxin-Antibody Conjugates
- Conjugates, Cytotoxin-Antibody
- Cytotoxin Antibody Conjugates
- Immunotoxin
- Antibody-Toxin Hybrids
- Antibody Toxin Hybrids
- Hybrids, Antibody-Toxin
- Affinotoxins
- Antibody-Toxin Conjugates
- Antibody Toxin Conjugates
- Conjugates, Antibody-Toxin
- Toxin-Antibody Conjugates
- Conjugates, Toxin-Antibody
- Toxin Antibody Conjugates
- Toxin-Antibody Hybrids
- Hybrids, Toxin-Antibody
- Toxin Antibody Hybrids
- Monoclonal Antibody-Toxin Conjugates
- Antibody-Toxin Conjugates, Monoclonal
- Conjugates, Monoclonal Antibody-Toxin
- Monoclonal Antibody Toxin Conjugates
Toxins, Chimeric- Toxins, Chimeric
- Chimeric Toxins
- Toxin Conjugates
- Conjugates, Toxin
- Toxin Carriers
- Carriers, Toxin
- Toxin Conjugate
- Conjugate, Toxin
- Chimeric Toxin
- Toxin, Chimeric
- Toxin Carrier
- Carrier, Toxin
|
Below are MeSH descriptors whose meaning is more general than "Immunotoxins".
Below are MeSH descriptors whose meaning is more specific than "Immunotoxins".
This graph shows the total number of publications written about "Immunotoxins" by people in this website by year, and whether "Immunotoxins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 2 | 0 | 2 |
| 2006 | 2 | 2 | 4 |
| 2020 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Immunotoxins" by people in Profiles.
-
Effects of an environmentally relevant PCB-mixture on immune function, clinical chemistry, and thyroid hormone levels in adult female B6C3F1 mice. J Toxicol Environ Health A. 2021 04 03; 84(7):279-297.
-
Effects of hypocretin-1 in 192-IgG-saporin-lesioned rats. Eur J Neurosci. 2006 Oct; 24(7):2084-8.
-
Gemtuzumab ozogamicin-associated sinusoidal obstructive syndrome (SOS): an overview from the research on adverse drug events and reports (RADAR) project. Leuk Res. 2007 May; 31(5):599-604.
-
Convection-enhanced delivery of immunotoxins and radioisotopes for treatment of malignant gliomas. Neurosurg Focus. 2006 Apr 15; 20(4):E13.
-
Fresh frozen plasma and platelet concentrates may increase plasma anti-diphtheria toxin IgG concentrations: Implications for diphtheria fusion protein therapy. Cancer Immunol Immunother. 2006 Aug; 55(8):928-32.
-
Minocycline protects basal forebrain cholinergic neurons from mu p75-saporin immunotoxic lesioning. Eur J Neurosci. 2004 Jun; 19(12):3305-16.
-
Effects of hypocretin2-saporin and antidopamine-beta-hydroxylase-saporin neurotoxic lesions of the dorsolateral pons on sleep and muscle tone. Eur J Neurosci. 2004 May; 19(10):2741-52.
-
Relationship between CSF hypocretin levels and hypocretin neuronal loss. Exp Neurol. 2003 Dec; 184(2):1010-6.
-
Role of subplate neurons in functional maturation of visual cortical columns. Science. 2003 Jul 25; 301(5632):521-5.
-
Bone marrow purging studies in acute myelogenous leukemia using the recombinant anti-CD33 immunotoxin HuM195/rGel. Biol Blood Marrow Transplant. 2003 Jun; 9(6):364-72.