"Antipyrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
| Descriptor ID |
D000983
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| MeSH Number(s) |
D03.383.129.539.850.088
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Antipyrine".
Below are MeSH descriptors whose meaning is more specific than "Antipyrine".
This graph shows the total number of publications written about "Antipyrine" by people in this website by year, and whether "Antipyrine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
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Below are the most recent publications written about "Antipyrine" by people in Profiles.
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Antipyrine pharmacokinetics in the tail-suspended rat model. J Pharmacol Exp Ther. 1995 Jul; 274(1):345-52.
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Metabolic cage isolation reduces antipyrine clearance in rats. J Pharm Pharmacol. 1994 Jul; 46(7):581-4.
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Serum antipyrine concentrations determined by micellar electrokinetic capillary chromatography. J Chromatogr. 1993 Dec 08; 622(1):98-102.
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Lack of in vivo evidence of a cytochrome P450 metabolite participating in aminoglycoside nephrotoxicity. Biochem Pharmacol. 1993 Feb 09; 45(3):780-2.
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Effect of experimental hemorrhagic shock on hepatic drug elimination. Crit Care Med. 1992 Jun; 20(6):810-5.
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Effect of cobalt protoporphyrin on hepatic drug-metabolizing enzymes. Specificity for cytochrome P-450. Biochem Pharmacol. 1989 Jun 15; 38(12):2027-38.