"Hemidesmosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An anchoring junction of the cell to a non-cellular substrate, similar in morphology to halves of DESMOSOMES. They are composed of specialized areas of the plasma membrane where INTERMEDIATE FILAMENTS bind on the cytoplasmic face to the transmembrane linkers, INTEGRINS, via intracellular attachment proteins, while the extracellular domain of the integrins binds to EXTRACELLULAR MATRIX PROTEINS.
Descriptor ID |
D022002
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MeSH Number(s) |
A11.284.149.165.165.360
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hemidesmosomes".
Below are MeSH descriptors whose meaning is more specific than "Hemidesmosomes".
This graph shows the total number of publications written about "Hemidesmosomes" by people in this website by year, and whether "Hemidesmosomes" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hemidesmosomes" by people in Profiles.
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Neutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoid. Matrix Biol. 2012 Jan; 31(1):38-44.