"Bisbenzimidazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
| Descriptor ID |
D006690
|
| MeSH Number(s) |
D03.633.100.103.145
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Bisbenzimidazole".
Below are MeSH descriptors whose meaning is more specific than "Bisbenzimidazole".
This graph shows the total number of publications written about "Bisbenzimidazole" by people in this website by year, and whether "Bisbenzimidazole" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 0 | 3 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bisbenzimidazole" by people in Profiles.
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Gram-negative synergy and mechanism of action of alkynyl bisbenzimidazoles. Sci Rep. 2019 10 02; 9(1):14171.
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New Application of Neomycin B-Bisbenzimidazole Hybrids as Antifungal Agents. ACS Infect Dis. 2018 02 09; 4(2):196-207.
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Impact of Linker Length and Composition on Fragment Binding and Cell Permeation: Story of a Bisbenzimidazole Dye Fragment. Biochemistry. 2017 Dec 12; 56(49):6434-6447.
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Selective Inhibition of Escherichia coli RNA and DNA Topoisomerase I by Hoechst 33258 Derived Mono- and Bisbenzimidazoles. J Med Chem. 2017 06 22; 60(12):4904-4922.
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Linker dependent intercalation of bisbenzimidazole-aminosugars in an RNA duplex; selectivity in RNA vs. DNA binding. Bioorg Med Chem Lett. 2016 12 15; 26(24):5989-5994.
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Recognition of RNA duplex by a neomycin-Hoechst 33258 conjugate. Bioorg Med Chem. 2014 Apr 01; 22(7):2327-32.
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Targeting C-myc G-quadruplex: dual recognition by aminosugar-bisbenzimidazoles with varying linker lengths. Molecules. 2013 Nov 18; 18(11):14228-40.
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Recognition of HIV-TAR RNA using neomycin-benzimidazole conjugates. Bioorg Med Chem Lett. 2013 Oct 15; 23(20):5689-93.
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Triple recognition of B-DNA by a neomycin-Hoechst 33258-pyrene conjugate. Biochemistry. 2010 Jan 26; 49(3):452-69.
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Triple recognition of B-DNA. Bioorg Med Chem Lett. 2009 Sep 01; 19(17):4974-9.