"Interleukin-1alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.
Descriptor ID |
D053582
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MeSH Number(s) |
D12.644.276.374.465.010.300 D12.644.276.374.500.400.300 D12.776.467.374.465.010.300 D12.776.467.374.500.400.300 D23.529.374.465.131.300 D23.529.374.500.400.300
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Concept/Terms |
Interleukin-1alpha- Interleukin-1alpha
- Interleukin 1alpha
- IL-1 alpha
- Interleukin-1 alpha
- Interleukin 1 alpha
- Hematopoietin-1
- Hematopoietin 1
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1alpha".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1alpha".
This graph shows the total number of publications written about "Interleukin-1alpha" by people in this website by year, and whether "Interleukin-1alpha" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 2 | 1 | 3 |
2009 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-1alpha" by people in Profiles.
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IL-1a and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cells. PLoS Pathog. 2014 Mar; 10(3):e1004035.
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IL-1 gene polymorphisms, secretion in gingival crevicular fluid, and speed of human orthodontic tooth movement. Orthod Craniofac Res. 2009 May; 12(2):129-40.
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Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis. Arthritis Rheum. 2008 Dec; 58(12):3941-50.
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Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis. Cancer Cell. 2008 Aug 12; 14(2):156-65.
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Immunocompetent murine model of cancer cachexia for head and neck squamous cell carcinoma. Head Neck. 2008 Mar; 30(3):320-6.