Neuroleptic Malignant Syndrome
"Neuroleptic Malignant Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Descriptor ID |
D009459
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| MeSH Number(s) |
C10.228.140.079.737 C10.720.737 C25.723.705.600
|
| Concept/Terms |
Neuroleptic Malignant Syndrome- Neuroleptic Malignant Syndrome
- Neuroleptic Malignant Syndromes
- Syndrome, Neuroleptic Malignant
- Syndromes, Neuroleptic Malignant
- NMS (Neuroleptic Malignant Syndrome)
- NMSs (Neuroleptic Malignant Syndrome)
Neuroleptic-Induced Neuroleptic Malignant Syndrome- Neuroleptic-Induced Neuroleptic Malignant Syndrome
- Neuroleptic Induced Neuroleptic Malignant Syndrome
- Neuroleptic-Malignant Syndrome, Neuroleptic Induced
- Neuroleptic Malignant Syndrome, Neuroleptic Induced
|
Below are MeSH descriptors whose meaning is more general than "Neuroleptic Malignant Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Neuroleptic Malignant Syndrome".
This graph shows the total number of publications written about "Neuroleptic Malignant Syndrome" by people in this website by year, and whether "Neuroleptic Malignant Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neuroleptic Malignant Syndrome" by people in Profiles.
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The Role of Amantadine Withdrawal in 3 Cases of Treatment-Refractory Altered Mental Status. J Psychiatr Pract. 2017 05; 23(3):191-199.
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A Woman in Her 60s With Fever and Altered Mental Status in a Psychiatric Hospital. Chest. 2016 Dec; 150(6):e171-e174.
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Malignant catatonia in a patient with bipolar disorder, B12 deficiency, and neuroleptic malignant syndrome: one cause or three? J Psychiatr Pract. 2009 Sep; 15(5):415-22.
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Fatal neurotoxic response to neuroleptic medications: case report and review of the literature. Am J Forensic Med Pathol. 2007 Jun; 28(2):116-20.
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Multiple ECT late in the course of neuroleptic malignant syndrome. Convuls Ther. 1997 Dec; 13(4):269-73.
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Facilitating prompt diagnosis and treatment of the neuroleptic malignant syndrome. Clin Pharmacol Ther. 1991 Nov; 50(5 Pt 1):580-6.