Endocardial Cushion Defects
"Endocardial Cushion Defects" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A spectrum of septal defects involving the ATRIAL SEPTUM; VENTRICULAR SEPTUM; and the atrioventricular valves (TRICUSPID VALVE; BICUSPID VALVE). These defects are due to incomplete growth and fusion of the ENDOCARDIAL CUSHIONS which are important in the formation of two atrioventricular canals, site of future atrioventricular valves.
| Descriptor ID |
D004694
|
| MeSH Number(s) |
C14.240.400.560.350 C14.280.400.560.350 C16.131.240.400.560.350
|
| Concept/Terms |
Endocardial Cushion Defects- Endocardial Cushion Defects
- Cushion Defect, Endocardial
- Cushion Defects, Endocardial
- Defect, Endocardial Cushion
- Defects, Endocardial Cushion
- Endocardial Cushion Defect
|
Below are MeSH descriptors whose meaning is more general than "Endocardial Cushion Defects".
Below are MeSH descriptors whose meaning is more specific than "Endocardial Cushion Defects".
This graph shows the total number of publications written about "Endocardial Cushion Defects" by people in this website by year, and whether "Endocardial Cushion Defects" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endocardial Cushion Defects" by people in Profiles.
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The pathogenesis of atrial and atrioventricular septal defects with special emphasis on the role of the dorsal mesenchymal protrusion. Differentiation. 2012 Jul; 84(1):117-30.
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Chick embryos exposed to trichloroethylene in an ex ovo culture model show selective defects in early endocardial cushion tissue formation. Birth Defects Res A Clin Mol Teratol. 2006 Jul; 76(7):517-27.
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Left-right lineage analysis of AV cushion tissue in normal and laterality defective Xenopus hearts. Anat Rec A Discov Mol Cell Evol Biol. 2005 Dec; 287(2):1176-82.
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Genetic aspects of atrioventricular septal defects. Am J Med Genet. 2000; 97(4):289-96.
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RXR alpha deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice. J Clin Invest. 1996 Sep 15; 98(6):1332-43.
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Morphogenetic alterations during endocardial cushion development in the trisomy 16 (Down syndrome) mouse. Pediatr Cardiol. 1996 Jan-Feb; 17(1):21-30.
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Molecular regulation of atrioventricular valvuloseptal morphogenesis. Circ Res. 1995 Jul; 77(1):1-6.