"Brain Death" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)
| Descriptor ID |
D001926
|
| MeSH Number(s) |
C10.228.140.151 C10.597.606.358.800.200.100 C23.550.260.159
|
| Concept/Terms |
Brain Death- Brain Death
- Death, Brain
- Brain Dead
- Brain Deads
- Coma Depasse
|
Below are MeSH descriptors whose meaning is more general than "Brain Death".
Below are MeSH descriptors whose meaning is more specific than "Brain Death".
This graph shows the total number of publications written about "Brain Death" by people in this website by year, and whether "Brain Death" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 3 | 3 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 3 | 0 | 3 |
| 2016 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Brain Death" by people in Profiles.
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Hemodynamic Effects of High-dose Levothyroxine and Methylprednisolone in Brain-dead Potential Organ Donors. Transplantation. 2022 08 01; 106(8):1677-1689.
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In Situ Pre-Treatment of Vascularized Composite Allografts With a Targeted Complement Inhibitor Protects Against Brain Death and Ischemia Reperfusion Induced Injuries. Front Immunol. 2021; 12:630581.
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Management of the neurologically deceased organ donor: A Canadian clinical practice guideline. CMAJ. 2020 04 06; 192(14):E361-E369.
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Donor pretreatment with nebulized complement C3a receptor antagonist mitigates brain-death induced immunological injury post-lung transplant. Am J Transplant. 2018 10; 18(10):2417-2428.
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Thyroid hormone use during cardiac transplant organ procurement. Clin Transplant. 2016 12; 30(12):1578-1583.
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Does Declaration of Brain Death Serve the Best Interest of Organ Donors Rather Than Merely Facilitating Organ Transplantation? Ann Thorac Surg. 2016 Jun; 101(6):2053-8.
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Resource utilization associated with procurement of transplantable organs from donors that do not meet OPTN eligible death criteria. Transplantation. 2014 May 27; 97(10):1043-8.
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Consequences of the Dead Donor Rule. Ann Thorac Surg. 2014 Apr; 97(4):1131-2.
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The paradox of the dead donor rule: increasing death on the waiting list. Am J Bioeth. 2014; 14(8):21-3.
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Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts. Circulation. 2013 Mar 26; 127(12):1290-9.