"alpha-MSH" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.
| Descriptor ID |
D000521
|
| MeSH Number(s) |
D06.472.699.327.935.179 D06.472.699.327.935.531.750.050 D06.472.699.631.525.600.179 D06.472.699.631.525.600.531.750.050 D12.644.400.400.935.179 D12.644.400.400.935.531.750.050 D12.644.400.460.050 D12.644.548.365.935.179 D12.644.548.365.935.531.750.050 D12.644.548.691.525.690.179 D12.644.548.691.525.690.531.750.050 D12.776.631.650.405.935.179 D12.776.631.650.405.935.531.750.050 D12.776.631.650.460.050
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| Concept/Terms |
alpha-MSH- alpha-MSH
- alpha MSH
- alpha-Melanotropin
- alpha Melanotropin
- Acetylated ACTH (1-13)NH2
- alpha-Melanocyte-Stimulating Hormone
- Hormone, alpha-Melanocyte-Stimulating
- alpha Melanocyte Stimulating Hormone
- MSH, alpha
ACTH (1-13)NH2- ACTH (1-13)NH2
- (Desacetyl)alpha-MSH
- DE-alpha-MSH
- MSH, (Desacetyl)alpha-
- Des-Acetyl MSH
- MSH, Des-Acetyl
- Desacetyl alpha-MSH
- Desacetyl alpha MSH
- alpha-MSH, Desacetyl
- Desacetyl alpha-Melanocyte-Stimulating Hormone
- Desacetyl alpha Melanocyte Stimulating Hormone
- Hormone, Desacetyl alpha-Melanocyte-Stimulating
- alpha-Melanocyte-Stimulating Hormone, Desacetyl
- (Des-Acetyl)-alpha-MSH
- Adrenocorticotropin (1-13)NH2
|
Below are MeSH descriptors whose meaning is more general than "alpha-MSH".
Below are MeSH descriptors whose meaning is more specific than "alpha-MSH".
This graph shows the total number of publications written about "alpha-MSH" by people in this website by year, and whether "alpha-MSH" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "alpha-MSH" by people in Profiles.
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Interventional treatments for Hailey-Hailey disease. J Am Acad Dermatol. 2017 Mar; 76(3):551-558.e3.
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Molecular characterization of human melanocortin-3 receptor ligand-receptor interaction. Biochemistry. 2006 Jan 31; 45(4):1128-37.
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Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist. Proc Natl Acad Sci U S A. 2004 Jul 06; 101(27):10201-4.
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Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra. Int J Impot Res. 2004 Apr; 16(2):135-42.
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Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients with mild-to-moderate erectile dysfunction. Int J Impot Res. 2004 Feb; 16(1):51-9.
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PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003 Jun; 994:96-102.
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Epitopes located in spatially separate domains of each neurofilament subunit are present in Parkinson's disease Lewy bodies. J Comp Neurol. 1991 Jul 01; 309(1):150-60.