"Diazepam" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
Descriptor ID |
D003975
|
MeSH Number(s) |
D03.633.100.079.080.070.216
|
Concept/Terms |
Diazepam- Diazepam
- 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
|
Below are MeSH descriptors whose meaning is more general than "Diazepam".
Below are MeSH descriptors whose meaning is more specific than "Diazepam".
This graph shows the total number of publications written about "Diazepam" by people in this website by year, and whether "Diazepam" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
1996 | 1 | 0 | 1 |
1997 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2006 | 1 | 2 | 3 |
2008 | 0 | 1 | 1 |
2017 | 2 | 0 | 2 |
2019 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Diazepam" by people in Profiles.
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Patterns of benzodiazepine underdosing in the Established Status Epilepticus Treatment Trial. Epilepsia. 2021 03; 62(3):795-806.
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Photopotentiation of the GABAA receptor with caged diazepam. Proc Natl Acad Sci U S A. 2019 10 15; 116(42):21176-21184.
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Postoperative Pain Management following Thoracic Outlet Decompression. Ann Vasc Surg. 2017 Oct; 44:241-244.
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Increasing efficacy and reducing side effects in treatment of chronic anal fissures: A study of topical diazepam therapy. Medicine (Baltimore). 2017 May; 96(20):e6853.
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The anti-convulsant stiripentol acts directly on the GABA(A) receptor as a positive allosteric modulator. Neuropharmacology. 2009 Jan; 56(1):190-7.
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The role of delta opioid receptors in the anxiolytic actions of benzodiazepines. Pharmacol Biochem Behav. 2006 Nov; 85(3):545-54.
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Microinjection of naltrexone into the central, but not the basolateral, amygdala blocks the anxiolytic effects of diazepam in the plus maze. Neuropsychopharmacology. 2006 Jun; 31(6):1227-40.
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Risk factors for delirium tremens: a retrospective chart review. Am J Addict. 2006 May-Jun; 15(3):213-9.
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Anxiolytic effects of diazepam and ethanol in two behavioral models: comparison of males and females. Pharmacol Biochem Behav. 2004 Jul; 78(3):445-58.
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A double-blind comparison of abecarnil and diazepam in the treatment of uncomplicated alcohol withdrawal. Psychopharmacology (Berl). 1997 May; 131(2):123-9.