"Osteoprotegerin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
| Descriptor ID |
D053244
|
| MeSH Number(s) |
D12.776.543.750.705.852.760.949.249
|
| Concept/Terms |
Osteoprotegerin- Osteoprotegerin
- Osteoclastogenesis Inhibitory Factor
- Receptors, Tumor Necrosis Factor, Member 11b
- Follicular Dendritic Cell-Derived Receptor-1
- Follicular Dendritic Cell Derived Receptor 1
- Tumor Necrosis Factor Receptor Superfamily, Member 11b
- FDCR-1 Protein
- FDCR 1 Protein
- OCIF Protein
- Tumor Necrosis Factor Receptor 11b
|
Below are MeSH descriptors whose meaning is more general than "Osteoprotegerin".
Below are MeSH descriptors whose meaning is more specific than "Osteoprotegerin".
This graph shows the total number of publications written about "Osteoprotegerin" by people in this website by year, and whether "Osteoprotegerin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Osteoprotegerin" by people in Profiles.
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Autoregulation of RANK ligand in oral squamous cell carcinoma tumor cells. J Cell Physiol. 2018 08; 233(8):6125-6134.
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A new role for OPG: putting RANKL in its place. J Bone Miner Res. 2010 Sep; 25(9):1905-6.
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NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest. 2008 Nov; 118(11):3775-89.
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Osteogenic responses in fibroblasts activated by elastin degradation products and transforming growth factor-beta1: role of myofibroblasts in vascular calcification. Am J Pathol. 2007 Jul; 171(1):116-23.
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Osteoprotegerin overexpression by breast cancer cells enhances orthotopic and osseous tumor growth and contrasts with that delivered therapeutically. Cancer Res. 2006 Apr 01; 66(7):3620-8.
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Mechanical stimulation effects on functional end effectors in osteoblastic MG-63 cells. J Biomech. 2006; 39(8):1419-27.
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Annexin II stimulates RANKL expression through MAPK. J Bone Miner Res. 2005 Jul; 20(7):1161-7.
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Modulation of TRAIL signaling complex. Vitam Horm. 2004; 67:81-99.