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Cole, David
One or more keywords matched the following items that are connected to
Cole, David
Item Type
Name
Academic Article
T-cell receptor repertoire in matched MART-1 peptide-stimulated peripheral blood lymphocytes and tumor-infiltrating lymphocytes.
Academic Article
Primary T-cell and activated macrophage response associated with tumor protection using peptide/poly-N-acetyl glucosamine vaccination.
Academic Article
CD8-independent tumor cell recognition is a property of the T cell receptor and not the T cell.
Academic Article
Paracrine release of IL-12 stimulates IFN-gamma production and dramatically enhances the antigen-specific T cell response after vaccination with a novel peptide-based cancer vaccine.
Academic Article
Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8+CD62Lhi cells and results in superior anti-tumor activity in a tolerogenic murine model.
Academic Article
Loss of T cell-mediated antitumor immunity after construct-specific downregulation of retrovirally encoded T-cell receptor expression in vivo.
Academic Article
Sustained release of granulocyte-macrophage colony-stimulating factor from a modular peptide-based cancer vaccine alters vaccine microenvironment and enhances the antigen-specific T-cell response.
Academic Article
Cyclophosphamide induces bone marrow to yield higher numbers of precursor dendritic cells in vitro capable of functional antigen presentation to T cells in vivo.
Academic Article
Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.
Academic Article
Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host.
Academic Article
CD8(+) T cells sabotage their own memory potential through IFN-?-dependent modification of the IL-12/IL-15 receptor a axis on dendritic cells.
Academic Article
A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice.
Academic Article
Transfer of TCR genes into mature T cells is accompanied by the maintenance of parental T cell avidity.
Academic Article
Mechanisms of enhanced antigen-specific T cell response following vaccination with a novel peptide-based cancer vaccine and systemic interleukin-2 (IL-2).
Academic Article
Identification of MART-1-specific T-cell receptors: T cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope.
Academic Article
Histopathological analysis of metastatic melanoma deposits in patients receiving adoptive immunotherapy with tumor-infiltrating lymphocytes.
Academic Article
Identification of a T-cell receptor from a therapeutic murine T-cell clone.
Academic Article
Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity.
Academic Article
The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu.
Academic Article
Accurate discrimination of pancreatic ductal adenocarcinoma and chronic pancreatitis using multimarker expression data and samples obtained by minimally invasive fine needle aspiration.
Academic Article
Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells.
Academic Article
The TLR3 agonist poly(I:C) targets CD8+ T cells and augments their antigen-specific responses upon their adoptive transfer into na?ve recipient mice.
Academic Article
Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C).
Academic Article
Dendritic cell recovery post-lymphodepletion: a potential mechanism for anti-cancer adoptive T cell therapy and vaccination.
Academic Article
Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide.
Academic Article
Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen.
Academic Article
Melanoma-associated tumor antigens and their clinical relevance to immunotherapy.
Concept
T-Lymphocytes, Cytotoxic
Concept
CD8-Positive T-Lymphocytes
Concept
Lymphocyte Count
Concept
T-Lymphocytes, Regulatory
Concept
T-Lymphocyte Subsets
Concept
Epitopes, T-Lymphocyte
Concept
Lymphocytes, Tumor-Infiltrating
Concept
T-Lymphocytes
Concept
Lymphocyte Activation
Concept
Lymphocyte Depletion
Concept
CD4-Positive T-Lymphocytes
Concept
B-Lymphocytes
Academic Article
G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses.
Academic Article
IL-12 conditioning improves retrovirally mediated transduction efficiency of CD8+ T cells.
Academic Article
Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.
Academic Article
The inducible costimulator augments Tc17 cell responses to self and tumor tissue.
Academic Article
Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling.
Academic Article
Lack of p53 Augments Antitumor Functions in Cytolytic T Cells.
Academic Article
IL-2Ra mediates temporal regulation of IL-2 signaling and enhances immunotherapy.
Academic Article
Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Ra Dependent.
Academic Article
Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model.
Academic Article
Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance.
Academic Article
Effect of administration timing of postchemotherapy granulocyte colony-stimulating factor on host-immune cell recovery and CD8+ T-cell response.
Academic Article
Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.
Academic Article
Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer.
Academic Article
Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8+ T Cells.
Academic Article
Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection.
Academic Article
Novel TCR-based biologics: mobilising T cells to warm 'cold' tumours.
Concept
Myelin and Lymphocyte-Associated Proteolipid Proteins
Search Criteria
Lymphocytes