Search Result Details

Back to Search Results
This page shows the details of why an item matched the keywords from your search.
Search Results
Grabowski, Gregory
One or more keywords matched the following items that are connected to Grabowski, Gregory
Item TypeName
Concept Saposins
Academic Article Saposin C is required for normal resistance of acid beta-glucosidase to proteolytic degradation.
Academic Article Gaucher disease mouse models: point mutations at the acid beta-glucosidase locus combined with low-level prosaposin expression lead to disease variants.
Academic Article Saposin C: neuronal effect and CNS delivery by liposomes.
Academic Article Combined saposin C and D deficiencies in mice lead to a neuronopathic phenotype, glucosylceramide and alpha-hydroxy ceramide accumulation, and altered prosaposin trafficking.
Academic Article Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice.
Academic Article Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice.
Academic Article Specific saposin C deficiency: CNS impairment and acid beta-glucosidase effects in the mouse.
Academic Article Neuronopathic Gaucher disease in the mouse: viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits.
Academic Article The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin.
Academic Article Comparative therapeutic effects of velaglucerase alfa and imiglucerase in a Gaucher disease mouse model.
Academic Article Saposins utilize two strategies for lipid transfer and CD1 antigen presentation.
Academic Article Tissue-specific effects of saposin A and saposin B on glycosphingolipid degradation in mutant mice.
Academic Article Substrate compositional variation with tissue/region and Gba1 mutations in mouse models--implications for Gaucher disease.
Academic Article Altered autophagy in the mice with a deficiency of saposin A and saposin B.
Academic Article Spiral ganglion degeneration and hearing loss as a consequence of satellite cell death in saposin B-deficient mice.
Academic Article Role of saposin C and D in auditory and vestibular function.
Academic Article Combination of acid ?-glucosidase mutation and Saposin C deficiency in mice reveals Gba1 mutation dependent and tissue-specific disease phenotype.
Academic Article Ex vivo localization of the mouse saposin C activation region for acid beta-glucosidase.
Academic Article Analyses of temporal regulatory elements of the prosaposin gene in transgenic mice.
Academic Article Systemic enzyme delivery by blood-brain barrier-penetrating SapC-DOPS nanovesicles for treatment of neuronopathic Gaucher disease.
Search Criteria
  • Saposins