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Olsen, Shaun
One or more keywords matched the following items that are connected to Olsen, Shaun
Item TypeName
Concept Ubiquitin-Activating Enzymes
Concept Ubiquitin-Conjugating Enzymes
Academic Article Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes.
Academic Article Active site remodelling accompanies thioester bond formation in the SUMO E1.
Academic Article S.?pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.
Academic Article Domain alternation and active site remodeling are conserved structural features of ubiquitin E1.
Academic Article Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI.
Academic Article Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity.
Academic Article UFM1-Activating Enzyme 5 (Uba5) Requires an Extension to Get the Job Done Right.
Academic Article Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme.
Academic Article Structural basis for adenylation and thioester bond formation in the ubiquitin E1.
Academic Article Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34.
Academic Article Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification.
Academic Article Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity.
Academic Article Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6.
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  • Enzymes