Lynn M Schnapp

TitleDirector, Division of Pulmonary and Critical Care Medicine
InstitutionMedical University of South Carolina
DepartmentPulmonary
AddressP.O. Box MSC 630
Clinical Science Bldg. - 96 Jonathan Lucas St.
Phone843-792-3167
Fax843-792-0732
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    Lynn Schnapp, M.D., is the George R. And Elaine Love Professor and Chair of Medicine, at School of Medicine and Public Health, University of Wisconsin-Madison, and is the former Division Chief of the Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine at the Medical University of South Carolina. She was previously Professor of Pulmonary and Critical Care Medicine at University of Washington in Seattle, where she directed the Respiratory, Cell, and Molecular Biology track of the Pulmonary & Critical Care Medicine Fellowship. Prior to that, she held faculty positions at the Mount Sinai School of Medicine in New York, NY, and at the University of California, San Francisco.

    Dr. Schnapp leads an active research program focused on lung injury and repair. Her research began in the field of integrin biology and has evolved to examine matrix remodeling in the normal and injured lung. She continues her research into the role of lung pericytes and other stromal cells in the pathogenesis of fibrosis. She also plans to continue her analysis of bronchoalveolar lavage fluid from patients with different lung diseases using cutting-edge methodologies in proteomics to identify new biomarkers and causative pathways.

    Dr. Schnapp also focuses on enhancing career development and mentoring opportunities.. At the University of Washington, she was part of the leadership team of the Clinical and Translational Science Award (CTSA) program, developing programs to enhance team science, translational research, and career development opportunities throughout the region.

    Dr. Schnapp has held several leadership positions within the American Thoracic Society (ATS). She recently completed her term as President of the ATS. Prior roles include Chair of the Respiratory Cell, Molecular Biology Assembly and as member of the Board of Directors of ATS.

    Dr. Schnapp received her undergraduate education at the Massachusetts Institute of Technology and earned her medical degree from the University of Pennsylvania, where she also completed her medical residency. She completed a Pulmonary and Critical Care Fellowship at the University of California, San Francisco.
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    Lung, Pulmonary

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Downey GP, Rivera MP, Schnapp LM, Petrache I, Roman J, Collishaw KJ. Considerations in Selecting Venues for the ATS International Conference: Balancing Competing Priorities of the Society's Diverse Membership. Ann Am Thorac Soc. 2023 Mar 08. PMID: 36884216.
      Citations:    Fields:    
    2. Wilson CL, Hung CF, Burkel BM, Ponik SM, Gharib SA, Schnapp LM. Nephronectin is required to maintain right lung lobar separation during embryonic development. Am J Physiol Lung Cell Mol Physiol. 2023 Mar 01; 324(3):L335-L344. PMID: 36719987; PMCID: PMC10027138.
      Citations:    Fields:    Translation:Animals
    3. Li P, Wu Y, Goodwin AJ, Halushka PV, Wilson CL, Schnapp LM, Fan H. Generation of a new immortalized human lung pericyte cell line: a promising tool for human lung pericyte studies. Lab Invest. 2021 May; 101(5):625-635. PMID: 36775384.
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    4. Burns KEA, Moss M, Lorens E, Jose EKA, Martin CM, Viglianti EM, Fox-Robichaud A, Mathews KS, Akgun K, Jain S, Gershengorn H, Mehta S, Han JE, Martin GS, Liebler JM, Stapleton RD, Trachuk P, Vranas KC, Chua A, Herridge MS, Tsang JLY, Biehl M, Burnham EL, Chen JT, Attia EF, Mohamed A, Harkins MS, Soriano SM, Maddux A, West JC, Badke AR, Bagshaw SM, Binnie A, Carlos WG, ?oruh B, Crothers K, D'Aragon F, Denson JL, Drover JW, Eschun G, Geagea A, Griesdale D, Hadler R, Hancock J, Hasmatali J, Kaul B, Kerlin MP, Kohn R, Kutsogiannis DJ, Matson SM, Morris PE, Paunovic B, Peltan ID, Piquette D, Pirzadeh M, Pulchan K, Schnapp LM, Sessler CN, Smith H, Sy E, Thirugnanam S, McDonald RK, McPherson KA, Kraft M, Spiegel M, Dodek PM, Diversity-Related Research Committee of the Women in Critical Care (WICC) Interest Group of the Amer. Wellness and Coping of Physicians Who Worked in ICUs During the Pandemic: A Multicenter Cross-Sectional North American Survey. Crit Care Med. 2022 12 01; 50(12):1689-1700. PMID: 36300945; PMCID: PMC9668381.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    5. Downey GP, Rivera MP, Schnapp L, Petrache I, Roman J, Collishaw K. Be the Change: Advancing Lung Health and Closing the Global Healthcare Gap. Am J Respir Crit Care Med. 2022 09 15; 206(6):667-669. PMID: 36112773.
      Citations:    Fields:    Translation:Humans
    6. Wu Y, Mealer C, Schutt S, Wilson CL, Bastian D, Sofi MH, Zhang M, Luo Z, Choi HJ, Yang K, Tian L, Nguyen H, Helke K, Schnapp LM, Wang H, Yu XZ, Wu Y, Mealer C, Schutt S, Wilson CL, Bastian D, Sofi MH, Zhang M, Luo Z, Choi HJ, Yang K, Tian L, Nguyen H, Helke K, Schnapp LM, Wang H, Yu XZ. MicroRNA-31 regulates T-cell metabolism via HIF1a and promotes chronic GVHD pathogenesis in mice. Blood Adv. 2022 05 24; 6(10):3036-3052. PMID: 35073581; PMCID: PMC9131913.
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    7. Wilson CL, Hung CF, Schnapp LM, Wilson CL, Hung CF, Schnapp LM. Endotoxin-induced acute lung injury in mice with postnatal deletion of nephronectin. PLoS One. 2022; 17(5):e0268398. PMID: 35552565; PMCID: PMC9097991.
      Citations:    Fields:    Translation:AnimalsCells
    8. Hung CF, Wilson CL, Chow YH, Liles WC, Gharib SA, Altemeier WA, Schnapp LM, Hung CF, Wilson CL, Chow YH, Liles WC, Gharib SA, Altemeier WA, Schnapp LM. Effect of lung pericyte-like cell ablation on the bleomycin model of injury and repair. Am J Physiol Lung Cell Mol Physiol. 2022 04 01; 322(4):L607-L616. PMID: 35196901; PMCID: PMC8993536.
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    9. Crothers K, Schnapp LM, Crothers K, Schnapp LM. World AIDS Day: 40 years of an evolving pulmonary landscape. Am J Physiol Lung Cell Mol Physiol. 2021 12 01; 321(6):L1059-L1061. PMID: 34755570; PMCID: PMC8715025.
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    10. Li P, Wu Y, Goodwin AJ, Halushka PV, Wilson CL, Schnapp LM, Fan H, Li P, Wu Y, Goodwin AJ, Halushka PV, Wilson CL, Schnapp LM, Fan H. Generation of a new immortalized human lung pericyte cell line: a promising tool for human lung pericyte studies. Lab Invest. 2021 05; 101(5):625-635. PMID: 33446892; PMCID: PMC8068576.
      Citations:    
    11. Mohan A, Neequaye N, Malur A, Soliman E, McPeek M, Leffler N, Ogburn D, Tokarz DA, Knudson W, Gharib SA, Schnapp LM, Barna BP, Thomassen MJ, Mohan A, Neequaye N, Malur A, Soliman E, McPeek M, Leffler N, Ogburn D, Tokarz DA, Knudson W, Gharib SA, Schnapp LM, Barna BP, Thomassen MJ. Matrix Metalloproteinase-12 Is Required for Granuloma Progression. Front Immunol. 2020; 11:553949. PMID: 33072094; PMCID: PMC7531023.
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    12. Stephenson SE, Wilson CL, Bond NG, Kaur A, Alvarez X, Midkiff CC, Schnapp LM, Stephenson SE, Wilson CL, Bond NG, Kaur A, Alvarez X, Midkiff CC, Schnapp LM. Pericytes as novel targets for HIV/SIV infection in the lung. Am J Physiol Lung Cell Mol Physiol. 2020 11 01; 319(5):L848-L853. PMID: 32901522; PMCID: PMC7789975.
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    13. Schnapp LM, Steiner MJ, Davis SD, Schnapp LM, Steiner MJ, Davis SD. Basic Primer for Finances in Academic Adult?and Pediatric Pulmonary Divisions. Chest. 2020 02; 157(2):363-368. PMID: 31593691; PMCID: PMC7005376.
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    14. Nguyen HB, Thomson C, Jarjour NN, Dixon AE, Liesching TN, Schnapp LM, Madison JM, Murin S, Glenny R, Kaminski N, Nguyen HB, Thomson C, Jarjour NN, Dixon AE, Liesching TN, Schnapp LM, Madison JM, Murin S, Glenny R, Kaminski N, Leadership Working Group of the Association of Pulmonary, Critical Care, and Sleep Division Director. Leading Change and Negotiation Strategies for Division Leaders in Clinical Medicine. Chest. 2019 12; 156(6):1246-1253. PMID: 31299244.
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    15. Roman J, Barnes TR, Kervitsky DJ, Cosgrove GP, Doherty DE, Tager AM, Richeldi L, White ES, Brenner DA, Schnapp LM, Hewitson TD, Jugdutt BI, McKinsey TA, Tosi JD, Crane S, Brown KK, Roman J, Barnes TR, Kervitsky DJ, Cosgrove GP, Doherty DE, Tager AM, Richeldi L, White ES, Brenner DA, Schnapp LM, Hewitson TD, Jugdutt BI, McKinsey TA, Tosi JD, Crane S, Brown KK, Fibrosis Across Organs Symposium Working Group. The Fibrosis Across Organs Symposium: A Roadmap for Future Research Priorities. Am J Med Sci. 2019 05; 357(5):405-410. PMID: 31010467; PMCID: PMC7219529.
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    16. Hung CF, Wilson CL, Schnapp LM, Hung CF, Wilson CL, Schnapp LM. Pericytes in the Lung. Adv Exp Med Biol. 2019; 1122:41-58. PMID: 30937862.
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    17. Thomson CC, Riekert KA, Bates CK, Jena AB, Borok Z, McCallister JW, Schnapp LM, Lama VN, Kraft M, Davis SD, Finn P, Carson SS, Beck JM, Powell CA, Tanoue LT, Kaminski N, Dixon AE, Thomson CC, Riekert KA, Bates CK, Jena AB, Borok Z, McCallister JW, Schnapp LM, Lama VN, Kraft M, Davis SD, Finn P, Carson SS, Beck JM, Powell CA, Tanoue LT, Kaminski N, Dixon AE. Addressing Gender Inequality in Our Disciplines: Report from the Association of Pulmonary, Critical Care, and Sleep Division Chiefs. Ann Am Thorac Soc. 2018 12; 15(12):1382-1390. PMID: 30153425.
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    18. Li P, Zhou Y, Goodwin AJ, Cook JA, Halushka PV, Zhang XK, Wilson CL, Schnapp LM, Zingarelli B, Fan H, Li P, Zhou Y, Goodwin AJ, Cook JA, Halushka PV, Zhang XK, Wilson CL, Schnapp LM, Zingarelli B, Fan H. Fli-1 Governs Pericyte Dysfunction in a Murine Model of Sepsis. J Infect Dis. 2018 11 05; 218(12):1995-2005. PMID: 30053030; PMCID: PMC6217724.
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    19. Wilson CL, Stephenson SE, Higuero JP, Feghali-Bostwick C, Hung CF, Schnapp LM, Wilson CL, Stephenson SE, Higuero JP, Feghali-Bostwick C, Hung CF, Schnapp LM. Characterization of human PDGFR-?-positive pericytes from IPF and non-IPF lungs. Am J Physiol Lung Cell Mol Physiol. 2018 12 01; 315(6):L991-L1002. PMID: 30335500; PMCID: PMC6337011.
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    20. Rajan A, Persson BD, Frängsmyr L, Olofsson A, Sandblad L, Heino J, Takada Y, Mould AP, Schnapp LM, Gall J, Arnberg N, Rajan A, Persson BD, Fr?ngsmyr L, Olofsson A, Sandblad L, Heino J, Takada Y, Mould AP, Schnapp LM, Gall J, Arnberg N. Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells. Sci Rep. 2018 07 03; 8(1):10019. PMID: 29968781; PMCID: PMC6030200.
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    21. Orr RK, Hoehn JL, Col NF, Nguyen HB, Thomson CC, Kaminski N, Schnapp LM, Madison JM, Glenny RW, Dixon AE, Leadership Working Group of the Association of Pulmonary, Critical Care, and Sleep Division Director. Leadership Primer for Current and Aspiring Pulmonary, Critical Care, and Sleep Medicine Academic Division Chiefs. Ann Am Thorac Soc. 2018 06; 15(6):655-661. PMID: 29485911.
      Citations:    
    22. Hung CF, Wilson CL, Chow YH, Schnapp LM, Hung CF, Wilson CL, Chow YH, Schnapp LM. Role of integrin alpha8 in murine model of lung fibrosis. PLoS One. 2018; 13(5):e0197937. PMID: 29813125; PMCID: PMC5973593.
      Citations:    
    23. Schutt SD, Wu Y, Tang CH, Bastian D, Nguyen H, Sofi MH, Zhang M, Liu C, Helke K, Wilson C, Schnapp LM, Del Valle JR, Hu CC, Yu XZ, Schutt SD, Wu Y, Tang CH, Bastian D, Nguyen H, Sofi MH, Zhang M, Liu C, Helke K, Wilson C, Schnapp LM, Del Valle JR, Hu CC, Yu XZ. Inhibition of the IRE-1a/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice. Blood Adv. 2018 02 27; 2(4):414-427. PMID: 29483082; PMCID: PMC5858472.
      Citations:    
    24. Stephenson SE, Wilson CL, Crothers K, Attia EF, Wongtrakool C, Petrache I, Schnapp LM, Stephenson SE, Wilson CL, Crothers K, Attia EF, Wongtrakool C, Petrache I, Schnapp LM. Impact of HIV infection on a1-antitrypsin in the lung. Am J Physiol Lung Cell Mol Physiol. 2018 04 01; 314(4):L583-L592. PMID: 29351445; PMCID: PMC5966776.
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    25. Mohan A, Malur A, McPeek M, Barna BP, Schnapp LM, Thomassen MJ, Gharib SA, Mohan A, Malur A, McPeek M, Barna BP, Schnapp LM, Thomassen MJ, Gharib SA. Transcriptional survey of alveolar macrophages in a murine model of chronic granulomatous inflammation reveals common themes with human sarcoidosis. Am J Physiol Lung Cell Mol Physiol. 2018 04 01; 314(4):L617-L625. PMID: 29212802; PMCID: PMC5966779.
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    26. Beiko T, Janech MG, Alekseyenko AV, Atkinson C, Coxson HO, Barth JL, Stephenson SE, Wilson CL, Schnapp LM, Barker A, Brantly M, Sandhaus RA, Silverman EK, Stoller JK, Trapnell B, Charlie S, Beiko T, Janech MG, Alekseyenko AV, Atkinson C, Coxson HO, Barth JL, Stephenson SE, Wilson CL, Schnapp LM, Barker A, Brantly M, Sandhaus RA, Silverman EK, Stoller JK, Trapnell B, Charlie S. Serum Proteins Associated with Emphysema Progression in Severe Alpha-1 Antitrypsin Deficiency. Chronic Obstr Pulm Dis. 2017 Jul 15; 4(3):204-216. PMID: 28848932; PMCID: PMC5556912.
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    27. Hung CF, Mittelsteadt KL, Brauer R, McKinney BL, Hallstrand TS, Parks WC, Chen P, Schnapp LM, Liles WC, Duffield JS, Altemeier WA, Hung CF, Mittelsteadt KL, Brauer R, McKinney BL, Hallstrand TS, Parks WC, Chen P, Schnapp LM, Liles WC, Duffield JS, Altemeier WA. Lung pericyte-like cells are functional interstitial immune sentinel cells. Am J Physiol Lung Cell Mol Physiol. 2017 Apr 01; 312(4):L556-L567. PMID: 28188224; PMCID: PMC5407093.
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    28. Hung CF, Chow YH, Liles WC, Altemeier WA, Schnapp LM, Hung CF, Chow YH, Liles WC, Altemeier WA, Schnapp LM. Ablation of Pericyte-Like Cells in Lungs by Oropharyngeal Aspiration of Diphtheria Toxin. Am J Respir Cell Mol Biol. 2017 Feb; 56(2):160-167. PMID: 27779900; PMCID: PMC5359647.
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    29. Gharib SA, Malur A, Huizar I, Barna BP, Kavuru MS, Schnapp LM, Thomassen MJ, Gharib SA, Malur A, Huizar I, Barna BP, Kavuru MS, Schnapp LM, Thomassen MJ. Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells. Respir Res. 2016 07 26; 17(1):93. PMID: 27460362; PMCID: PMC4962428.
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    30. Crothers K, Petrache I, Wongtrakool C, Lee PJ, Schnapp LM, Gharib SA, Crothers K, Petrache I, Wongtrakool C, Lee PJ, Schnapp LM, Gharib SA. Widespread activation of immunity and pro-inflammatory programs in peripheral blood leukocytes of HIV-infected patients with impaired lung gas exchange. Physiol Rep. 2016 Apr; 4(8). PMID: 27117807; PMCID: PMC4848721.
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    31. Attia EF, Jolley SE, Crothers K, Schnapp LM, Liles WC, Attia EF, Jolley SE, Crothers K, Schnapp LM, Liles WC. Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Elevated in Bronchoalveolar Lavage Fluid of Patients with Acute Respiratory Distress Syndrome. PLoS One. 2016; 11(2):e0149687. PMID: 26919714; PMCID: PMC4768838.
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    32. Nadig NR, Vanderbilt AA, Ford DW, Schnapp LM, Pastis NJ, Nadig NR, Vanderbilt AA, Ford DW, Schnapp LM, Pastis NJ. Variability in structure of university pulmonary/critical care fellowships and retention of fellows in academic medicine. Ann Am Thorac Soc. 2015 Apr; 12(4):553-6. PMID: 25715099; PMCID: PMC6913069.
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    33. Grazioli S, Gil S, An D, Kajikawa O, Farnand AW, Hanson JF, Birkland T, Chen P, Duffield J, Schnapp LM, Altemeier WA, Matute-Bello G, Grazioli S, Gil S, An D, Kajikawa O, Farnand AW, Hanson JF, Birkland T, Chen P, Duffield J, Schnapp LM, Altemeier WA, Matute-Bello G. CYR61 (CCN1) overexpression induces lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15; 308(8):L759-65. PMID: 25713320; PMCID: PMC4398872.
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    34. Attia EF, Akgün KM, Wongtrakool C, Goetz MB, Rodriguez-Barradas MC, Rimland D, Brown ST, Soo Hoo GW, Kim J, Lee PJ, Schnapp LM, Sharafkhaneh A, Justice AC, Crothers K, Attia EF, Akg?n KM, Wongtrakool C, Goetz MB, Rodriguez-Barradas MC, Rimland D, Brown ST, Soo Hoo GW, Kim J, Lee PJ, Schnapp LM, Sharafkhaneh A, Justice AC, Crothers K. Increased risk of radiographic emphysema in HIV is associated with elevated soluble CD14 and nadir CD4. Chest. 2014 Dec; 146(6):1543-1553. PMID: 25080158; PMCID: PMC4251616.
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    35. Nguyen EV, Gharib SA, Schnapp LM, Goodlett DR, Nguyen EV, Gharib SA, Schnapp LM, Goodlett DR. Shotgun MS proteomic analysis of bronchoalveolar lavage fluid in normal subjects. Proteomics Clin Appl. 2014 Oct; 8(9-10):737-47. PMID: 24616423; PMCID: PMC4239657.
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    36. Rohani MG, Chow YH, Razumova MV, Ash S, Hung CF, Schnapp LM, Rohani MG, Chow YH, Razumova MV, Ash S, Hung CF, Schnapp LM. uPARAP function in cutaneous wound repair. PLoS One. 2014; 9(3):e92660. PMID: 24663959; PMCID: PMC3963911.
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    37. Nguyen EV, Gharib SA, Crothers K, Chow YH, Park DR, Goodlett DR, Schnapp LM, Nguyen EV, Gharib SA, Crothers K, Chow YH, Park DR, Goodlett DR, Schnapp LM. Proteomic landscape of bronchoalveolar lavage fluid in human immunodeficiency virus infection. Am J Physiol Lung Cell Mol Physiol. 2014 Jan 01; 306(1):L35-42. PMID: 24213920; PMCID: PMC3920210.
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    38. Hung CF, Rohani MG, Lee SS, Chen P, Schnapp LM, Hung CF, Rohani MG, Lee SS, Chen P, Schnapp LM. Role of IGF-1 pathway in lung fibroblast activation. Respir Res. 2013 Oct 08; 14:102. PMID: 24103846; PMCID: PMC3840605.
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    39. Hung C, Linn G, Chow YH, Kobayashi A, Mittelsteadt K, Altemeier WA, Gharib SA, Schnapp LM, Duffield JS, Hung C, Linn G, Chow YH, Kobayashi A, Mittelsteadt K, Altemeier WA, Gharib SA, Schnapp LM, Duffield JS. Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis. Am J Respir Crit Care Med. 2013 Oct 01; 188(7):820-30. PMID: 23924232; PMCID: PMC3826269.
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    40. Hacker BM, Subramanian L, Schnapp LM, Hacker BM, Subramanian L, Schnapp LM. Strategies for mentor matching: lessons learned. Clin Transl Sci. 2013 Oct; 6(5):414-6. PMID: 24127933; PMCID: PMC3802119.
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    41. Nguyen EV, Gharib SA, Palazzo SJ, Chow YH, Goodlett DR, Schnapp LM, Nguyen EV, Gharib SA, Palazzo SJ, Chow YH, Goodlett DR, Schnapp LM. Proteomic profiling of bronchoalveolar lavage fluid in critically ill patients with ventilator-associated pneumonia. PLoS One. 2013; 8(3):e58782. PMID: 23505561; PMCID: PMC3591362.
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    42. Palazzo SJ, Simpson TA, Simmons JM, Schnapp LM, Palazzo SJ, Simpson TA, Simmons JM, Schnapp LM. Soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) as a diagnostic marker of ventilator-associated pneumonia. Respir Care. 2012 Dec; 57(12):2052-8. PMID: 22613763; PMCID: PMC4432465.
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    43. Schnapp LM, Rotschy L, Hall TE, Crowley S, O'Rourke M, Schnapp LM, Rotschy L, Hall TE, Crowley S, O'Rourke M. How to talk to strangers: facilitating knowledge sharing within translational health teams with the Toolbox dialogue method. Transl Behav Med. 2012 Dec; 2(4):469-79. PMID: 24073147; PMCID: PMC3717935.
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    44. Song EH, Manganiello MJ, Chow YH, Ghosn B, Convertine AJ, Stayton PS, Schnapp LM, Ratner DM, Song EH, Manganiello MJ, Chow YH, Ghosn B, Convertine AJ, Stayton PS, Schnapp LM, Ratner DM. In vivo targeting of alveolar macrophages via RAFT-based glycopolymers. Biomaterials. 2012 Oct; 33(28):6889-97. PMID: 22770567; PMCID: PMC3449172.
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    45. Orr RK, Hoehn JL, Col NF, Chow YH, Liu L, Schwartz B, Harlan JM, Schnapp LM. Short communication: adhesion pathways utilized by HIV-infected lymphocytes. AIDS Res Hum Retroviruses. 2012 Dec; 28(12):1557-60. PMID: 22394260; PMCID: PMC3505057.
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    46. Kim TH, Chow YH, Gill SE, Schnapp LM, Kim TH, Chow YH, Gill SE, Schnapp LM. Effect of insulin-like growth factor blockade on hyperoxia-induced lung injury. Am J Respir Cell Mol Biol. 2012 Sep; 47(3):372-8. PMID: 22493012; PMCID: PMC3488689.
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    47. Palazzo SJ, Simpson T, Schnapp LM, Palazzo SJ, Simpson T, Schnapp LM. Triggering receptor expressed on myeloid cells type 1 as a potential therapeutic target in sepsis. Dimens Crit Care Nurs. 2012 Jan-Feb; 31(1):1-6. PMID: 22156803; PMCID: PMC4754668.
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    48. Orr RK, Hoehn JL, Col NF, Bundesmann MM, Wagner TE, Chow YH, Altemeier WA, Steinbach T, Schnapp LM. Role of urokinase plasminogen activator receptor-associated protein in mouse lung. Am J Respir Cell Mol Biol. 2012 Feb; 46(2):233-9. PMID: 21940816; PMCID: PMC3297169.
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    49. Palazzo SJ, Simpson T, Schnapp L, Palazzo SJ, Simpson T, Schnapp L. Biomarkers for ventilator-associated pneumonia: review of the literature. Heart Lung. 2011 Jul-Aug; 40(4):293-8. PMID: 21419491; PMCID: PMC3129391.
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    50. Schnapp LM, Schnapp LM. Smoke signals in the intensive care unit. Crit Care Med. 2011 Jan; 39(1):197-8. PMID: 21178534.
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    51. Orr RK, Hoehn JL, Col NF, Chow YH, Zhu XD, Liu L, Schwartz BR, Huang XZ, Harlan JM, Schnapp LM. Role of Cdk4 in lymphocyte function and allergen response. Cell Cycle. 2010 Dec 15; 9(24):4922-30. PMID: 21150327; PMCID: PMC3047815.
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    52. Gharib SA, Nguyen E, Altemeier WA, Shaffer SA, Doneanu CE, Goodlett DR, Schnapp LM, Gharib SA, Nguyen E, Altemeier WA, Shaffer SA, Doneanu CE, Goodlett DR, Schnapp LM. Of mice and men: comparative proteomics of bronchoalveolar fluid. Eur Respir J. 2010 Jun; 35(6):1388-95. PMID: 20032019; PMCID: PMC3049194.
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    53. Benjamin JT, Gaston DC, Halloran BA, Schnapp LM, Zent R, Prince LS, Benjamin JT, Gaston DC, Halloran BA, Schnapp LM, Zent R, Prince LS. The role of integrin alpha8beta1 in fetal lung morphogenesis and injury. Dev Biol. 2009 Nov 15; 335(2):407-17. PMID: 19769957; PMCID: PMC2783258.
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    54. Benoit YD, Lussier C, Ducharme PA, Sivret S, Schnapp LM, Basora N, Beaulieu JF, Benoit YD, Lussier C, Ducharme PA, Sivret S, Schnapp LM, Basora N, Beaulieu JF. Integrin alpha8beta1 regulates adhesion, migration and proliferation of human intestinal crypt cells via a predominant RhoA/ROCK-dependent mechanism. Biol Cell. 2009 Sep 14; 101(12):695-708. PMID: 19527220; PMCID: PMC2782361.
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    55. Schnapp LM, Schnapp LM. Another Notch on the belt. Blood. 2009 Feb 19; 113(8):1615-6. PMID: 19228927.
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    56. Schnapp LM, Vaught M, Park DR, Rubenfeld G, Goodman RB, Hudson LD, Schnapp LM, Vaught M, Park DR, Rubenfeld G, Goodman RB, Hudson LD. Implementation and impact of a translational research training program in pulmonary and critical care medicine. Chest. 2009 Mar; 135(3):688-694. PMID: 19017887; PMCID: PMC3468153.
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    57. Choi JE, Lee SS, Sunde DA, Huizar I, Haugk KL, Thannickal VJ, Vittal R, Plymate SR, Schnapp LM, Choi JE, Lee SS, Sunde DA, Huizar I, Haugk KL, Thannickal VJ, Vittal R, Plymate SR, Schnapp LM. Insulin-like growth factor-I receptor blockade improves outcome in mouse model of lung injury. Am J Respir Crit Care Med. 2009 Feb 01; 179(3):212-9. PMID: 19011156; PMCID: PMC2633054.
      Citations:    
    58. Smith L, Wagner TE, Huizar I, Schnapp LM, Smith L, Wagner TE, Huizar I, Schnapp LM. uPARAP expression during murine lung development. Gene Expr Patterns. 2008 Sep; 8(7-8):486-93. PMID: 18639653; PMCID: PMC2613018.
      Citations:    
    59. Chen J, Ryu S, Gharib SA, Goodlett DR, Schnapp LM, Chen J, Ryu S, Gharib SA, Goodlett DR, Schnapp LM. Exploration of the normal human bronchoalveolar lavage fluid proteome. Proteomics Clin Appl. 2008 Apr; 2(4):585-95. PMID: 21136857; PMCID: PMC4432467.
      Citations:    
    60. Liu L, Schwartz B, Tsubota Y, Raines E, Kiyokawa H, Yonekawa K, Harlan JM, Schnapp LM, Liu L, Schwartz B, Tsubota Y, Raines E, Kiyokawa H, Yonekawa K, Harlan JM, Schnapp LM. Cyclin-dependent kinase inhibitors block leukocyte adhesion and migration. J Immunol. 2008 Feb 01; 180(3):1808-17. PMID: 18209078; PMCID: PMC4623328.
      Citations:    
    61. Wall RJ, Schnapp LM, Wall RJ, Schnapp LM. Radiation pneumonitis. Respir Care. 2006 Nov; 51(11):1255-60. PMID: 17067408.
      Citations:    
    62. Schnapp LM, Donohoe S, Chen J, Sunde DA, Kelly PM, Ruzinski J, Martin T, Goodlett DR, Schnapp LM, Donohoe S, Chen J, Sunde DA, Kelly PM, Ruzinski J, Martin T, Goodlett DR. Mining the acute respiratory distress syndrome proteome: identification of the insulin-like growth factor (IGF)/IGF-binding protein-3 pathway in acute lung injury. Am J Pathol. 2006 Jul; 169(1):86-95. PMID: 16816363; PMCID: PMC1698774.
      Citations:    
    63. Farias E, Lu M, Li X, Schnapp LM, Farias E, Lu M, Li X, Schnapp LM. Integrin alpha8beta1-fibronectin interactions promote cell survival via PI3 kinase pathway. Biochem Biophys Res Commun. 2005 Apr 01; 329(1):305-11. PMID: 15721307.
      Citations:    
    64. Ekwa-Ekoka C, Diaz GA, Carlson C, Hasegawa T, Samudrala R, Lim KC, Yabu JM, Levy B, Schnapp LM, Ekwa-Ekoka C, Diaz GA, Carlson C, Hasegawa T, Samudrala R, Lim KC, Yabu JM, Levy B, Schnapp LM. Genomic organization and sequence variation of the human integrin subunit alpha8 gene (ITGA8). Matrix Biol. 2004 Nov; 23(7):487-96. PMID: 15579315.
      Citations:    
    65. Cameron CE, Brown EL, Kuroiwa JM, Schnapp LM, Brouwer NL, Cameron CE, Brown EL, Kuroiwa JM, Schnapp LM, Brouwer NL. Treponema pallidum fibronectin-binding proteins. J Bacteriol. 2004 Oct; 186(20):7019-22. PMID: 15466055; PMCID: PMC522185.
      Citations:    
    66. Pal S, Schnapp LM, Pal S, Schnapp LM. HIV-infected lymphocytes regulate fibronectin synthesis by TGF beta 1 secretion. J Immunol. 2004 Mar 01; 172(5):3189-95. PMID: 14978126.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    67. Wagner TE, Frevert CW, Herzog EL, Schnapp LM, Wagner TE, Frevert CW, Herzog EL, Schnapp LM. Expression of the integrin subunit alpha8 in murine lung development. J Histochem Cytochem. 2003 Oct; 51(10):1307-15. PMID: 14500699.
      Citations: 11     Fields:    Translation:Animals
    68. Schnapp LM, Matosian M, Weisman I, Welsh CH, Schnapp LM, Matosian M, Weisman I, Welsh CH. A snapshot of pulmonary medicine at the turn of the century: the American Thoracic Society membership. Am J Respir Crit Care Med. 2003 May 01; 167(9):1176-80. PMID: 12522026.
      Citations: 1     Fields:    Translation:Humans
    69. Orr RK, Hoehn JL, Col NF, Greco G, Pal S, Pasqualini R, Schnapp LM. Matrix fibronectin increases HIV stability and infectivity. J Immunol. 2002 Jun 01; 168(11):5722-9. PMID: 12023372.
      Citations: 16     Fields:    Translation:HumansCells
    70. Thibault G, Lacombe MJ, Schnapp LM, Lacasse A, Bouzeghrane F, Lapalme G, Thibault G, Lacombe MJ, Schnapp LM, Lacasse A, Bouzeghrane F, Lapalme G. Upregulation of alpha(8)beta(1)-integrin in cardiac fibroblast by angiotensin II and transforming growth factor-beta1. Am J Physiol Cell Physiol. 2001 Nov; 281(5):C1457-67. PMID: 11600408.
      Citations: 18     Fields:    Translation:AnimalsCells
    71. Weintraub AS, Schnapp LM, Lin X, Taubman MB, Weintraub AS, Schnapp LM, Lin X, Taubman MB. Osteopontin deficiency in rat vascular smooth muscle cells is associated with an inability to adhere to collagen and increased apoptosis. Lab Invest. 2000 Nov; 80(11):1603-15. PMID: 11092521.
      Citations: 13     Fields:    Translation:Animals
    72. Benson DL, Schnapp LM, Shapiro L, Huntley GW, Benson DL, Schnapp LM, Shapiro L, Huntley GW. Making memories stick: cell-adhesion molecules in synaptic plasticity. Trends Cell Biol. 2000 Nov; 10(11):473-82. PMID: 11050419.
      Citations: 57     Fields:    Translation:AnimalsCells
    73. Schecter AD, Spirn B, Rossikhina M, Giesen PL, Bogdanov V, Fallon JT, Fisher EA, Schnapp LM, Nemerson Y, Taubman MB, Schecter AD, Spirn B, Rossikhina M, Giesen PL, Bogdanov V, Fallon JT, Fisher EA, Schnapp LM, Nemerson Y, Taubman MB. Release of active tissue factor by human arterial smooth muscle cells. Circ Res. 2000 Jul 21; 87(2):126-32. PMID: 10903996.
      Citations: 23     Fields:    Translation:HumansCells
    74. Levine D, Rockey DC, Milner TA, Breuss JM, Fallon JT, Schnapp LM, Levine D, Rockey DC, Milner TA, Breuss JM, Fallon JT, Schnapp LM. Expression of the integrin alpha8beta1 during pulmonary and hepatic fibrosis. Am J Pathol. 2000 Jun; 156(6):1927-35. PMID: 10854216; PMCID: PMC1850077.
      Citations: 34     Fields:    Translation:Animals
    75. Gladson CL, Stewart JE, Olman MA, Chang PL, Schnapp LM, Grammer JR, Benveniste EN, Gladson CL, Stewart JE, Olman MA, Chang PL, Schnapp LM, Grammer JR, Benveniste EN. Attachment of primary neonatal rat astrocytes to vitronectin is mediated by integrins alphavbeta5 and alpha8beta1: modulation by the type 1 plasminogen activator inhibitor. Neurosci Lett. 2000 Apr 07; 283(2):157-61. PMID: 10739899.
      Citations: 7     Fields:    Translation:AnimalsCells
    76. Tellier MC, Greco G, Klotman M, Mosoian A, Cara A, Arap W, Ruoslahti E, Pasqualini R, Schnapp LM, Tellier MC, Greco G, Klotman M, Mosoian A, Cara A, Arap W, Ruoslahti E, Pasqualini R, Schnapp LM. Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4+ T lymphocytes. J Immunol. 2000 Mar 15; 164(6):3236-45. PMID: 10706716.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    77. Hosono S, Luo X, Hyink DP, Schnapp LM, Wilson PD, Burrow CR, Reddy JC, Atweh GF, Licht JD, Hosono S, Luo X, Hyink DP, Schnapp LM, Wilson PD, Burrow CR, Reddy JC, Atweh GF, Licht JD. WT1 expression induces features of renal epithelial differentiation in mesenchymal fibroblasts. Oncogene. 1999 Jan 14; 18(2):417-27. PMID: 9927198.
      Citations: 13     Fields:    Translation:AnimalsCells
    78. Schnapp LM, Goswami S, Rienzi N, Koteliansky VE, Gotwals P, Schachter EN, Schnapp LM, Goswami S, Rienzi N, Koteliansky VE, Gotwals P, Schachter EN. Integrins inhibit angiotensin II-induced contraction in rat aortic rings. Regul Pept. 1998 Oct 16; 77(1-3):177-83. PMID: 9809813.
      Citations: 4     Fields:    Translation:AnimalsCells
    79. Schnapp LM, Schnapp LM. Elmer's glue, Elsie and you: clinical applications of adhesion molecules. Mt Sinai J Med. 1998 May; 65(3):224-31. PMID: 9615575.
      Citations:    Fields:    Translation:HumansCells
    80. Clyman RI, Goetzman BW, Chen YQ, Mauray F, Kramer RH, Pytela R, Schnapp LM, Clyman RI, Goetzman BW, Chen YQ, Mauray F, Kramer RH, Pytela R, Schnapp LM. Changes in endothelial cell and smooth muscle cell integrin expression during closure of the ductus arteriosus: an immunohistochemical comparison of the fetal, preterm newborn, and full-term newborn rhesus monkey ductus. Pediatr Res. 1996 Aug; 40(2):198-208. PMID: 8827767.
      Citations: 7     Fields:    Translation:Animals
    81. Huang L, Schnapp LM, Gruden JF, Hopewell PC, Stansell JD, Huang L, Schnapp LM, Gruden JF, Hopewell PC, Stansell JD. Presentation of AIDS-related pulmonary Kaposi's sarcoma diagnosed by bronchoscopy. Am J Respir Crit Care Med. 1996 Apr; 153(4 Pt 1):1385-90. PMID: 8616570.
      Citations: 21     Fields:    Translation:Humans
    82. Schnapp LM, Hatch N, Ramos DM, Klimanskaya IV, Sheppard D, Pytela R, Schnapp LM, Hatch N, Ramos DM, Klimanskaya IV, Sheppard D, Pytela R. The human integrin alpha 8 beta 1 functions as a receptor for tenascin, fibronectin, and vitronectin. J Biol Chem. 1995 Sep 29; 270(39):23196-202. PMID: 7559467.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    83. Schnapp LM, Chin DP, Szaflarski N, Matthay MA, Schnapp LM, Chin DP, Szaflarski N, Matthay MA. Frequency and importance of barotrauma in 100 patients with acute lung injury. Crit Care Med. 1995 Feb; 23(2):272-8. PMID: 7867352.
      Citations: 9     Fields:    Translation:Humans
    84. Schnapp LM, Breuss JM, Ramos DM, Sheppard D, Pytela R, Schnapp LM, Breuss JM, Ramos DM, Sheppard D, Pytela R. Sequence and tissue distribution of the human integrin alpha 8 subunit: a beta 1-associated alpha subunit expressed in smooth muscle cells. J Cell Sci. 1995 Feb; 108 ( Pt 2):537-44. PMID: 7768999.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    85. Schaumberg TH, Schnapp LM, Taylor KG, Golden JA, Schaumberg TH, Schnapp LM, Taylor KG, Golden JA. Diagnosis of Pneumocystis carinii infection in HIV-seropositive patients by identification of P carinii in pleural fluid. Chest. 1993 Jun; 103(6):1890-1. PMID: 8404120.
      Citations:    Fields:    Translation:HumansAnimals
    86. Ng VL, Geaghan SM, Leoung G, Shiboski S, Fahy J, Schnapp L, Yajko DM, Hopewell PC, Hadley WK, Ng VL, Geaghan SM, Leoung G, Shiboski S, Fahy J, Schnapp L, Yajko DM, Hopewell PC, Hadley WK. Lack of effect of prophylactic aerosolized pentamidine on the detection of Pneumocystis carinii in induced sputum or bronchoalveolar lavage specimens. Arch Pathol Lab Med. 1993 May; 117(5):493-6. PMID: 8489338.
      Citations: 2     Fields:    Translation:HumansAnimals
    87. Schnapp LM, Cohen NH, Schnapp LM, Cohen NH. Pulse oximetry. Uses and abuses. Chest. 1990 Nov; 98(5):1244-50. PMID: 2225973.
      Citations: 26     Fields:    Translation:Humans
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