Mucin-1

"Mucin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

Descriptor ID	D018396
MeSH Number(s)	D12.776.395.550.560 D12.776.395.560.631.115 D12.776.543.550.530 D23.050.285.050.300 D23.050.550.325.300 D23.101.140.075.300
Concept/Terms	Mucin-1 Mucin-1 Mucin 1 CA 15.3 Antigen Antigen, CA 15.3 Antigen CA-15-3 Antigen CA 15 3 CA-15-3, Antigen CA-15-3 Antigen Antigen, CA-15-3 Episialin CD227 Antigen Antigen, CD227 Polymorphic Epithelial Mucin Epithelial Membrane Antigen Antigen, Epithelial Membrane Membrane Antigen, Epithelial Muc1 Mucin Mucin, Muc1 Antigens, CD227 CD227 Antigens CA 15-3 Antigen Antigen, CA 15-3 CA 15 3 Antigen Epithelial Mucin, Polymorphic Mucin, Polymorphic Epithelial

Below are MeSH descriptors whose meaning is more general than "Mucin-1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Mucin-1 [D12.776.395.550.560]
Mucoproteins [D12.776.395.560]
Mucins [D12.776.395.560.631]
Mucin-1 [D12.776.395.560.631.115]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Mucin-1 [D12.776.543.550.530]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Neoplasm [D23.050.285]
Antigens, Tumor-Associated, Carbohydrate [D23.050.285.050]
Mucin-1 [D23.050.285.050.300]
Epitopes [D23.050.550]
Antigens, Tumor-Associated, Carbohydrate [D23.050.550.325]
Mucin-1 [D23.050.550.325.300]
Biomarkers [D23.101]
Biomarkers, Tumor [D23.101.140]
Antigens, Tumor-Associated, Carbohydrate [D23.101.140.075]
Mucin-1 [D23.101.140.075.300]

Below are MeSH descriptors whose meaning is related to "Mucin-1".

Below are MeSH descriptors whose meaning is more specific than "Mucin-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mucin-1" by people in this website by year, and whether "Mucin-1" was a major or minor topic of these publications.

Bar chart showing 18 publications over 13 distinct years, with a maximum of 3 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1997	0	1	1
1998	1	0	1
1999	2	0	2
2006	0	1	1
2007	0	1	1
2008	2	1	3
2009	2	0	2
2012	0	1	1
2013	2	0	2
2017	1	0	1
2018	1	0	1
2019	1	0	1

Below are the most recent publications written about "Mucin-1" by people in Profiles.

Volkmann ER, Tashkin DP, Kuwana M, Li N, Roth MD, Charles J, Hant FN, Bogatkevich GS, Akter T, Kim G, Goldin J, Khanna D, Clements PJ, Furst DE, Elashoff RM, Silver RM, Assassi S. Progression of Interstitial Lung Disease in Systemic Sclerosis: The Importance of Pneumoproteins Krebs von den Lungen 6 and CCL18. Arthritis Rheumatol. 2019 12; 71(12):2059-2067.

View in: PubMed
Carrell RK, Stanton RA, Ethier SP, LaRue AC, Soloff AC. ICOSL-augmented adenoviral-based vaccination induces a bipolar Th17/Th1 T cell response against unglycosylated MUC1 antigen. Vaccine. 2018 10 08; 36(42):6262-6269.

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Pandey JP, Namboodiri AM, Wolf B, Iwasaki M, Kasuga Y, Hamada GS, Tsugane S. Endogenous antibody responses to mucin 1 in a large multiethnic cohort of patients with breast cancer and healthy controls: Role of immunoglobulin and Fc? receptor genes. Immunobiology. 2018 02; 223(2):178-182.

View in: PubMed
Morse MA, Niedzwiecki D, Marshall JL, Garrett C, Chang DZ, Aklilu M, Crocenzi TS, Cole DJ, Dessureault S, Hobeika AC, Osada T, Onaitis M, Clary BM, Hsu D, Devi GR, Bulusu A, Annechiarico RP, Chadaram V, Clay TM, Lyerly HK. A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer. Ann Surg. 2013 Dec; 258(6):879-86.

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Pandey JP, Namboodiri AM, Kistner-Griffin E. IgG and Fc?R genotypes and humoral immunity to mucin 1 in prostate cancer. Hum Immunol. 2013 Aug; 74(8):1030-3.

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Nadig SN, Pedrosa I, Goldsmith JD, Callery MP, Vollmer CM. Clinical implications of mucinous nonneoplastic cysts of the pancreas. Pancreas. 2012 Apr; 41(3):441-6.

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Pandey JP, Nietert PJ, Klaamas K, Kurtenkov O. A genetic variant of immunoglobulin gamma2 is strongly associated with immunity to mucin 1 in patients with breast cancer. Cancer Immunol Immunother. 2009 Dec; 58(12):2025-9.

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Hant FN, Ludwicka-Bradley A, Wang HJ, Li N, Elashoff R, Tashkin DP, Silver RM. Surfactant protein D and KL-6 as serum biomarkers of interstitial lung disease in patients with scleroderma. J Rheumatol. 2009 Apr; 36(4):773-80.

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Varela JC, Atkinson C, Woolson R, Keane TE, Tomlinson S. Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection. Int J Cancer. 2008 Sep 15; 123(6):1357-63.

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Varela JC, Imai M, Atkinson C, Ohta R, Rapisardo M, Tomlinson S. Modulation of protective T cell immunity by complement inhibitor expression on tumor cells. Cancer Res. 2008 Aug 15; 68(16):6734-42.

View in: PubMed

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