"Mucin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.
| Descriptor ID |
D018396
|
| MeSH Number(s) |
D12.776.395.550.560 D12.776.395.560.631.115 D12.776.543.550.530 D23.050.285.050.300 D23.050.550.325.300 D23.101.140.075.300
|
| Concept/Terms |
Mucin-1- Mucin-1
- Mucin 1
- CA 15.3 Antigen
- Antigen, CA 15.3
- Antigen CA-15-3
- Antigen CA 15 3
- CA-15-3, Antigen
- CA-15-3 Antigen
- Antigen, CA-15-3
- Episialin
- CD227 Antigen
- Antigen, CD227
- Polymorphic Epithelial Mucin
- Epithelial Membrane Antigen
- Antigen, Epithelial Membrane
- Membrane Antigen, Epithelial
- Muc1 Mucin
- Mucin, Muc1
- Antigens, CD227
- CD227 Antigens
- CA 15-3 Antigen
- Antigen, CA 15-3
- CA 15 3 Antigen
- Epithelial Mucin, Polymorphic
- Mucin, Polymorphic Epithelial
|
Below are MeSH descriptors whose meaning is more general than "Mucin-1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Glycoproteins [D12.776.395]
- Membrane Glycoproteins [D12.776.395.550]
- Mucin-1 [D12.776.395.550.560]
- Mucoproteins [D12.776.395.560]
- Mucins [D12.776.395.560.631]
- Mucin-1 [D12.776.395.560.631.115]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Mucin-1 [D12.776.543.550.530]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Neoplasm [D23.050.285]
- Antigens, Tumor-Associated, Carbohydrate [D23.050.285.050]
- Mucin-1 [D23.050.285.050.300]
- Epitopes [D23.050.550]
- Antigens, Tumor-Associated, Carbohydrate [D23.050.550.325]
- Mucin-1 [D23.050.550.325.300]
- Biomarkers [D23.101]
- Biomarkers, Tumor [D23.101.140]
- Antigens, Tumor-Associated, Carbohydrate [D23.101.140.075]
- Mucin-1 [D23.101.140.075.300]
Below are MeSH descriptors whose meaning is more specific than "Mucin-1".
This graph shows the total number of publications written about "Mucin-1" by people in this website by year, and whether "Mucin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Mucin-1" by people in Profiles.
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Progression of Interstitial Lung Disease in Systemic Sclerosis: The Importance of Pneumoproteins Krebs von den Lungen 6 and CCL18. Arthritis Rheumatol. 2019 12; 71(12):2059-2067.
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ICOSL-augmented adenoviral-based vaccination induces a bipolar Th17/Th1 T cell response against unglycosylated MUC1 antigen. Vaccine. 2018 10 08; 36(42):6262-6269.
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Endogenous antibody responses to mucin 1 in a large multiethnic cohort of patients with breast cancer and healthy controls: Role of immunoglobulin and Fc? receptor genes. Immunobiology. 2018 02; 223(2):178-182.
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A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer. Ann Surg. 2013 Dec; 258(6):879-86.
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IgG and Fc?R genotypes and humoral immunity to mucin 1 in prostate cancer. Hum Immunol. 2013 Aug; 74(8):1030-3.
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Clinical implications of mucinous nonneoplastic cysts of the pancreas. Pancreas. 2012 Apr; 41(3):441-6.
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A genetic variant of immunoglobulin gamma2 is strongly associated with immunity to mucin 1 in patients with breast cancer. Cancer Immunol Immunother. 2009 Dec; 58(12):2025-9.
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Surfactant protein D and KL-6 as serum biomarkers of interstitial lung disease in patients with scleroderma. J Rheumatol. 2009 Apr; 36(4):773-80.
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Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection. Int J Cancer. 2008 Sep 15; 123(6):1357-63.
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Modulation of protective T cell immunity by complement inhibitor expression on tumor cells. Cancer Res. 2008 Aug 15; 68(16):6734-42.