"B-Cell Activating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.
| Descriptor ID |
D053264
|
| MeSH Number(s) |
D12.644.276.374.750.061 D12.776.395.191 D12.776.467.374.750.061 D12.776.543.550.193 D23.529.374.750.061
|
| Concept/Terms |
B-Cell Activating Factor- B-Cell Activating Factor
- Activating Factor, B-Cell
- B-Lymphocyte Activating Factor
- Activating Factor, B-Lymphocyte
- B Lymphocyte Activating Factor
- THANK Protein
- BAFF Ligand
- BLyS Protein
- B Cell Activating Factor
- B Lymphocyte Stimulator
- CD257 Antigen
- Antigen, CD257
- Antigens, CD257
- TNF and APOL-Related Leukocyte Expressed Ligand 1
- TNF and APOL Related Leukocyte Expressed Ligand 1
- TNF Superfamily, Member 13b
- Tumor Necrosis Factor Ligand Superfamily Member 13b
- CD257 Antigens
- TNFSF13B Protein
- TALL-1 Protein
- TALL 1 Protein
|
Below are MeSH descriptors whose meaning is more general than "B-Cell Activating Factor".
Below are MeSH descriptors whose meaning is more specific than "B-Cell Activating Factor".
This graph shows the total number of publications written about "B-Cell Activating Factor" by people in this website by year, and whether "B-Cell Activating Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "B-Cell Activating Factor" by people in Profiles.
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Estrogen receptor signal in regulation of B cell activation during diverse immune responses. Int J Biochem Cell Biol. 2015 Nov; 68:42-7.
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Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation. J Exp Med. 2014 Jan 13; 211(1):45-56.
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Allogenic mesenchymal stem cell transplantation ameliorates nephritis in lupus mice via inhibition of B-cell activation. Cell Transplant. 2013; 22(12):2279-90.
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IFN-a confers resistance of systemic lupus erythematosus nephritis to therapy in NZB/W F1 mice. J Immunol. 2011 Aug 01; 187(3):1506-13.
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A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. Blood. 2011 Aug 04; 118(5):1294-304.
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Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice. Arthritis Rheum. 2010 May; 62(5):1457-68.
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Increased expression of B cell-associated regulatory cytokines by glatiramer acetate in mice with experimental autoimmune encephalomyelitis. J Neuroimmunol. 2010 Feb 26; 219(1-2):47-53.
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Increased CD4+Foxp3+ T cells in BAFF-transgenic mice suppress T cell effector responses. J Immunol. 2009 Jan 15; 182(2):793-801.
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BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact. Proc Natl Acad Sci U S A. 2008 Oct 07; 105(40):15517-22.
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Prevention of murine antiphospholipid syndrome by BAFF blockade. Arthritis Rheum. 2008 Sep; 58(9):2824-34.