"Multiple Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Descriptor ID |
D009103
|
| MeSH Number(s) |
C10.114.375.500 C10.314.350.500 C20.111.258.250.500
|
| Concept/Terms |
Multiple Sclerosis- Multiple Sclerosis
- Sclerosis, Multiple
- Sclerosis, Disseminated
- Disseminated Sclerosis
- MS (Multiple Sclerosis)
|
Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".
This graph shows the total number of publications written about "Multiple Sclerosis" by people in this website by year, and whether "Multiple Sclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1994 | 3 | 0 | 3 |
| 1996 | 1 | 0 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 1 | 2 |
| 2006 | 4 | 1 | 5 |
| 2007 | 3 | 0 | 3 |
| 2008 | 1 | 2 | 3 |
| 2009 | 2 | 1 | 3 |
| 2010 | 5 | 0 | 5 |
| 2011 | 2 | 1 | 3 |
| 2012 | 4 | 0 | 4 |
| 2013 | 3 | 0 | 3 |
| 2014 | 8 | 0 | 8 |
| 2015 | 3 | 1 | 4 |
| 2016 | 3 | 2 | 5 |
| 2017 | 6 | 1 | 7 |
| 2018 | 4 | 0 | 4 |
| 2019 | 5 | 3 | 8 |
| 2020 | 1 | 0 | 1 |
| 2021 | 4 | 0 | 4 |
| 2022 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Multiple Sclerosis" by people in Profiles.
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Pineles SL, Henderson RJ, Repka MX, Heidary G, Liu GT, Waldman AT, Borchert MS, Khanna S, Graves JS, Collinge JE, Conley JA, Davis PL, Kraker RT, Cotter SA, Holmes JM. The Pediatric Optic Neuritis Prospective Outcomes Study: Two-Year Results. Ophthalmology. 2022 08; 129(8):856-864.
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Singh I, Kim J, Saxena N, Choi S, Islam SMT, Singh AK, Khan M, Won J. Vascular and immunopathological role of Asymmetric Dimethylarginine (ADMA) in Experimental Autoimmune Encephalomyelitis. Immunology. 2021 11; 164(3):602-616.
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Singh M, Gavidia R, Dunietz GL, Washnock-Schmid E, Romeo AR, Hershner S, Chervin RD, Braley TJ. Validation of an obstructive sleep apnea symptom inventory in persons with multiple sclerosis. Mult Scler. 2022 Feb; 28(2):280-288.
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Swanson CW, Richmond SB, Sharp BE, Fling BW. Middle-age people with multiple sclerosis demonstrate similar mobility characteristics to neurotypical older adults. Mult Scler Relat Disord. 2021 Jun; 51:102924.
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Krause JS, Li C, Backus D, Jarnecke M, Reed K, Rembert J, Rumrill P, Dismuke-Greer CE. Barriers and Facilitators to Employment: A Comparison of Participants With Multiple Sclerosis and Spinal Cord Injury. Arch Phys Med Rehabil. 2021 08; 102(8):1556-1561.
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Podbielska M, Szulc ZM, Ariga T, Pokryszko-Dragan A, Fortuna W, Bilinska M, Podemski R, Jaskiewicz E, Kurowska E, Yu RK, Hogan EL. Distinctive sphingolipid patterns in chronic multiple sclerosis lesions. J Lipid Res. 2020 11; 61(11):1464-1479.
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Workman CD, Kindred JH, Boles Ponto LL, Kamholz J, Rudroff T. The effects of chronic ?-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) use on cerebral glucose metabolism in multiple sclerosis: a pilot study. Appl Physiol Nutr Metab. 2020 Apr; 45(4):450-452.
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Yang X, Bam M, Nagarkatti PS, Nagarkatti M. Cannabidiol Regulates Gene Expression in Encephalitogenic T cells Using Histone Methylation and noncoding RNA during Experimental Autoimmune Encephalomyelitis. Sci Rep. 2019 10 31; 9(1):15780.
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Dasgupta S, Ray SK. Ceramide and Sphingosine Regulation of Myelinogenesis: Targeting Serine Palmitoyltransferase Using microRNA in Multiple Sclerosis. Int J Mol Sci. 2019 Oct 11; 20(20).
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Al-Ghezi ZZ, Miranda K, Nagarkatti M, Nagarkatti PS. Combination of Cannabinoids, ?9- Tetrahydrocannabinol and Cannabidiol, Ameliorates Experimental Multiple Sclerosis by Suppressing Neuroinflammation Through Regulation of miRNA-Mediated Signaling Pathways. Front Immunol. 2019; 10:1921.