"Dynamins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of high molecular weight GTP phosphohydrolases that play a direct role in vesicle transport. They associate with microtubule bundles (MICROTUBULES) and are believed to produce mechanical force via a process linked to GTP hydrolysis. This enzyme was formerly listed as EC 3.6.1.50.
Descriptor ID |
D034281
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MeSH Number(s) |
D08.811.277.040.330.200 D12.776.220.600.450.200 D12.776.543.990.400
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Concept/Terms |
GTPase-Deficient Dynamin- GTPase-Deficient Dynamin
- Dynamin, GTPase-Deficient
- GTPase Deficient Dynamin
- Dynamin, Alanine44 Substituted With Lysine
- Dynamin, Mutated Form, K44A
- Dynamin K44A
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Below are MeSH descriptors whose meaning is more general than "Dynamins".
Below are MeSH descriptors whose meaning is more specific than "Dynamins".
This graph shows the total number of publications written about "Dynamins" by people in this website by year, and whether "Dynamins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
1999 | 0 | 2 | 2 |
2000 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dynamins" by people in Profiles.
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Alternative splicing of GluN1 gates glycine site-dependent nonionotropic signaling by NMDAR receptors. Proc Natl Acad Sci U S A. 2021 07 06; 118(27).
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Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI. J Neurosci Res. 2018 12; 96(12):1900-1913.
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Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML. Blood. 2016 10 13; 128(15):1944-1958.
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HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE. Ann Rheum Dis. 2014 Oct; 73(10):1888-97.
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Awd, the homolog of metastasis suppressor gene Nm23, regulates Drosophila epithelial cell invasion. Mol Cell Biol. 2008 Mar; 28(6):1964-73.
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Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor. J Biol Chem. 2002 Jul 19; 277(29):26642-51.
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beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis. J Biol Chem. 2000 Apr 14; 275(15):11312-9.
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Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells. J Biol Chem. 1999 May 28; 274(22):15671-7.
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Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. J Biol Chem. 1999 Jan 15; 274(3):1185-8.
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Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J Biol Chem. 1998 Jan 09; 273(2):685-8.