3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
Descriptor ID |
D001498
|
MeSH Number(s) |
D03.383.725.203.600 D03.383.725.547.900
|
Concept/Terms |
Bay-R-5417- Bay-R-5417
- Bay R 5417
- BayR5417
- Bay R5417
- R5417, Bay
Bay-K-8644- Bay-K-8644
- Bay K 8644
- BayK8644
- Bay-K8644
- Bay K8644
- BK-8644
- BK 8644
- BK8644
|
Below are MeSH descriptors whose meaning is more general than "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester".
Below are MeSH descriptors whose meaning is more specific than "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester".
This graph shows the total number of publications written about "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester" by people in this website by year, and whether "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 2 | 2 |
2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester" by people in Profiles.
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Regulation of cardiac Ca(2+) channel by extracellular Na(+). Cell Calcium. 2011 Mar; 49(3):162-73.
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Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. Pharmacology. 1998 Nov; 57(5):249-60.
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Downstream defects in beta-adrenergic signaling and relation to myocyte contractility after cardioplegic arrest. J Thorac Cardiovasc Surg. 1998 Jan; 115(1):190-9.
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Effect of short-term ethanol treatment on voltage-dependent calcium channels in Kupffer cells. Hepatology. 1993 Aug; 18(2):400-5.
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Kupffer cells contain voltage-dependent calcium channels. Mol Pharmacol. 1992 Mar; 41(3):435-40.
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Interactions of dihydropyridine Ca2+ channel agonists with the human platelet thromboxane A2/prostaglandin H2 receptor. Eur J Pharmacol. 1991 Jan 25; 206(1):15-21.
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Chronic ethanol treatment alters omega-conotoxin and Bay K 8644 sensitive calcium channels in rat striatal synaptosomes. Alcohol. 1990 Jul-Aug; 7(4):279-84.
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Characterization of dihydropyridine-sensitive calcium channels in rat brain synaptosomes. Proc Natl Acad Sci U S A. 1988 Oct; 85(19):7389-93.
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Bay K 8644 stimulation of calcium entry and endogenous dopamine release in rat striatal synaptosomes antagonized by nimodipine. Brain Res. 1986 Apr 09; 370(2):397-400.