"Apamin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly neurotoxic polypeptide from the venom of the honey bee (Apis mellifera). It consists of 18 amino acids with two disulfide bridges and causes hyperexcitability resulting in convulsions and respiratory paralysis.
| Descriptor ID |
D001030
|
| MeSH Number(s) |
D20.888.065.115.060 D23.946.833.065.115.060
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Apamin".
Below are MeSH descriptors whose meaning is more specific than "Apamin".
This graph shows the total number of publications written about "Apamin" by people in this website by year, and whether "Apamin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apamin" by people in Profiles.
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KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction. Neuropsychopharmacology. 2015 Jul; 40(8):1928-39.
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SK channel-selective opening by SKA-31 induces hyperpolarization and decreases contractility in human urinary bladder smooth muscle. Am J Physiol Regul Integr Comp Physiol. 2013 Jan 15; 304(2):R155-63.
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SK but not IK channels regulate human detrusor smooth muscle spontaneous and nerve-evoked contractions. Am J Physiol Renal Physiol. 2012 Aug 15; 303(4):F559-68.
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Identification and functional characterization of the intermediate-conductance Ca(2+)-activated K(+) channel (IK-1) in biliary epithelium. Am J Physiol Gastrointest Liver Physiol. 2009 Nov; 297(5):G1009-18.
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Independent presynaptic and postsynaptic mechanisms regulate endocannabinoid signaling at multiple synapses in the ventral tegmental area. J Neurosci. 2004 Dec 08; 24(49):11070-8.
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Blockade of neurotensin-induced motor activity by inhibition of protein kinase. Psychopharmacology (Berl). 1994 Feb; 114(1):175-80.
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Effect of microinjections of apamin into the A10 dopamine region of rats: a behavioral and neurochemical analysis. J Pharmacol Exp Ther. 1990 Aug; 254(2):711-9.