"CD18 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.
| Descriptor ID |
D018821
|
| MeSH Number(s) |
D12.776.395.550.200.275.750 D12.776.543.550.200.275.750 D12.776.543.750.705.408.200.249 D12.776.543.750.705.408.600.100.750 D12.776.543.750.705.833.249.750 D23.050.301.264.894.118 D23.050.301.350.275.750 D23.101.100.894.118
|
| Concept/Terms |
CD18 Antigens- CD18 Antigens
- p150,95 beta-Subunit
- beta-Subunit, p150,95
- p150,95 beta Subunit
- Integrin beta2
- beta2, Integrin
- beta2 Integrin
- Integrin, beta2
- CD18 Antigen
- Antigens, CD18
|
Below are MeSH descriptors whose meaning is more general than "CD18 Antigens".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Glycoproteins [D12.776.395]
- Membrane Glycoproteins [D12.776.395.550]
- Cell Adhesion Molecules [D12.776.395.550.200]
- Integrin alphaXbeta2 [D12.776.395.550.200.275]
- CD18 Antigens [D12.776.395.550.200.275.750]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Cell Adhesion Molecules [D12.776.543.550.200]
- Integrin alphaXbeta2 [D12.776.543.550.200.275]
- CD18 Antigens [D12.776.543.550.200.275.750]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Integrins [D12.776.543.750.705.408]
- Integrin beta Chains [D12.776.543.750.705.408.200]
- CD18 Antigens [D12.776.543.750.705.408.200.249]
- Receptors, Leukocyte-Adhesion [D12.776.543.750.705.408.600]
- Integrin alphaXbeta2 [D12.776.543.750.705.408.600.100]
- CD18 Antigens [D12.776.543.750.705.408.600.100.750]
- Receptors, Complement [D12.776.543.750.705.833]
- Integrin alphaXbeta2 [D12.776.543.750.705.833.249]
- CD18 Antigens [D12.776.543.750.705.833.249.750]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- CD18 Antigens [D23.050.301.264.894.118]
- Cell Adhesion Molecules [D23.050.301.350]
- Integrin alphaXbeta2 [D23.050.301.350.275]
- CD18 Antigens [D23.050.301.350.275.750]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- CD18 Antigens [D23.101.100.894.118]
Below are MeSH descriptors whose meaning is more specific than "CD18 Antigens".
This graph shows the total number of publications written about "CD18 Antigens" by people in this website by year, and whether "CD18 Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "CD18 Antigens" by people in Profiles.
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a7 helix region of aI domain is crucial for integrin binding to endoplasmic reticulum chaperone gp96: a potential therapeutic target for cancer metastasis. J Biol Chem. 2013 Jun 21; 288(25):18243-8.
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Migration of CD11b+ accessory cells during murine lung regeneration. Stem Cell Res. 2013 May; 10(3):267-77.
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Metalloproteinase-mediated Shedding of Integrin ?2 promotes macrophage efflux from inflammatory sites. J Biol Chem. 2012 Feb 10; 287(7):4581-9.
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MMP-9 sheds the beta2 integrin subunit (CD18) from macrophages. Mol Cell Proteomics. 2009 May; 8(5):1044-60.
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Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins. J Immunol. 2001 Jun 15; 166(12):7534-42.
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Selective adhesion of macrophages to denatured forms of type I collagen is mediated by scavenger receptors. Matrix Biol. 2000 Feb; 19(1):61-71.
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Differential regulation of beta1 integrins by chemoattractants regulates neutrophil migration through fibrin. J Cell Biol. 1999 Mar 08; 144(5):1047-56.
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Anti-CD2 monoclonal antibody-induced receptor changes: down modulation of cell surface CD2. Transplantation. 1995 Apr 27; 59(8):1162-71.