Myogenic Regulatory Factors

"Myogenic Regulatory Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of muscle-specific transcription factors which bind to DNA in control regions and thus regulate myogenesis. All members of this family contain a conserved helix-loop-helix motif which is homologous to the myc family proteins. These factors are only found in skeletal muscle. Members include the myoD protein (MYOD PROTEIN); MYOGENIN; myf-5, and myf-6 (also called MRF4 or herculin).

Descriptor ID	D018006
MeSH Number(s)	D12.776.210.500.570 D12.776.260.103.750 D12.776.930.125.750
Concept/Terms	Myogenic Regulatory Factors Myogenic Regulatory Factors Factors, Myogenic Regulatory Regulatory Factors, Myogenic

Below are MeSH descriptors whose meaning is more general than "Myogenic Regulatory Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Contractile Proteins [D12.776.210]
Muscle Proteins [D12.776.210.500]
Myogenic Regulatory Factors [D12.776.210.500.570]
DNA-Binding Proteins [D12.776.260]
Basic Helix-Loop-Helix Transcription Factors [D12.776.260.103]
Myogenic Regulatory Factors [D12.776.260.103.750]
Transcription Factors [D12.776.930]
Basic Helix-Loop-Helix Transcription Factors [D12.776.930.125]
Myogenic Regulatory Factors [D12.776.930.125.750]

Below are MeSH descriptors whose meaning is related to "Myogenic Regulatory Factors".

Below are MeSH descriptors whose meaning is more specific than "Myogenic Regulatory Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Myogenic Regulatory Factors" by people in this website by year, and whether "Myogenic Regulatory Factors" was a major or minor topic of these publications.

Bar chart showing 10 publications over 8 distinct years, with a maximum of 3 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	0	1	1
2006	1	0	1
2008	1	2	3
2009	1	0	1
2010	1	0	1
2011	0	1	1
2012	0	1	1
2013	1	0	1

Below are the most recent publications written about "Myogenic Regulatory Factors" by people in Profiles.

Lockhart MM, Wirrig EE, Phelps AL, Ghatnekar AV, Barth JL, Norris RA, Wessels A. Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart. PLoS One. 2013; 8(2):e57073.

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Tsai NP, Wilkerson JR, Guo W, Maksimova MA, DeMartino GN, Cowan CW, Huber KM. Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95. Cell. 2012 Dec 21; 151(7):1581-94.

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Hosoyama T, Aslam MI, Abraham J, Prajapati SI, Nishijo K, Michalek JE, Zarzabal LA, Nelon LD, Guttridge DC, Rubin BP, Keller C. IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma. Clin Cancer Res. 2011 May 01; 17(9):2757-66.

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Pfeiffer BE, Zang T, Wilkerson JR, Taniguchi M, Maksimova MA, Smith LN, Cowan CW, Huber KM. Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2. Neuron. 2010 Apr 29; 66(2):191-7.

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Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT. MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr; 29(8):2193-204.

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Cowan CW, Taniguchi M, Hale CF. Regulation of synaptic connectivity with chronic cocaine. Am J Psychiatry. 2008 Nov; 165(11):1393.

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Chandler LJ, Kalivas PW. Neuroscience: Brain's defence against cocaine. Nature. 2008 Oct 09; 455(7214):743-4.

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Pulipparacharuvil S, Renthal W, Hale CF, Taniguchi M, Xiao G, Kumar A, Russo SJ, Sikder D, Dewey CM, Davis MM, Greengard P, Nairn AC, Nestler EJ, Cowan CW. Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron. 2008 Aug 28; 59(4):621-33.

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Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME. Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science. 2006 Feb 17; 311(5763):1008-12.

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Sturla LM, Cowan CW, Guenther L, Castellino RC, Kim JY, Pomeroy SL. A novel role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2 in medulloblastoma cell death. Cancer Res. 2005 Jul 01; 65(13):5683-9.

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