"fas Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.
| Descriptor ID |
D019014
|
| MeSH Number(s) |
D12.776.543.750.690.500 D12.776.543.750.705.852.760.195
|
| Concept/Terms |
fas Receptor- fas Receptor
- Receptor, fas
- fas Antigen
- fas Antigens
- APO-1 Antigen
- APO 1 Antigen
- CD95 Antigen
- TNFRSF6 Receptor
- Receptor, TNFRSF6
- Antigens, CD95
- Receptors, fas
- fas Receptors
- Tumor Necrosis Factor Receptor Superfamily, Member 6
- Fas Cell Surface Death Receptor
- CD95 Antigens
|
Below are MeSH descriptors whose meaning is more general than "fas Receptor".
Below are MeSH descriptors whose meaning is more specific than "fas Receptor".
This graph shows the total number of publications written about "fas Receptor" by people in this website by year, and whether "fas Receptor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 2 | 0 | 2 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 3 | 1 | 4 |
| 2001 | 2 | 3 | 5 |
| 2003 | 4 | 0 | 4 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 3 | 2 | 5 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "fas Receptor" by people in Profiles.
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T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy. J Clin Invest. 2019 02 25; 129(4):1551-1565.
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Microbiota promotes systemic T-cell survival through suppression of an apoptotic factor. Proc Natl Acad Sci U S A. 2017 05 23; 114(21):5497-5502.
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Human intrahepatic regulatory T cells are functional, require IL-2 from effector cells for survival, and are susceptible to Fas ligand-mediated apoptosis. Hepatology. 2016 07; 64(1):138-50.
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Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis. Sci Rep. 2015 Jul 22; 5:12463.
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Exposure to diethylstilbestrol during pregnancy modulates microRNA expression profile in mothers and fetuses reflecting oncogenic and immunological changes. Mol Pharmacol. 2015 May; 87(5):842-54.
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Plasmacytoid dendritic cells mediate synergistic effects of HIV and lipopolysaccharide on CD27+ IgD- memory B cell apoptosis. J Virol. 2014 Oct; 88(19):11430-41.
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Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression. BMC Cancer. 2014 Jan 15; 14:24.
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Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion. Nucleic Acids Res. 2013 May; 41(9):4949-62.
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Prenatal exposure to TCDD triggers significant modulation of microRNA expression profile in the thymus that affects consequent gene expression. PLoS One. 2012; 7(9):e45054.
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Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-?B motifs. J Pharmacol Exp Ther. 2012 Nov; 343(2):351-61.