Retinal Pigment Epithelium
"Retinal Pigment Epithelium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
| Descriptor ID |
D055213
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| MeSH Number(s) |
A09.371.670.500 A09.371.729.887
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinal Pigment Epithelium".
Below are MeSH descriptors whose meaning is more specific than "Retinal Pigment Epithelium".
This graph shows the total number of publications written about "Retinal Pigment Epithelium" by people in this website by year, and whether "Retinal Pigment Epithelium" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 2 | 3 | 5 |
| 2010 | 2 | 2 | 4 |
| 2011 | 5 | 0 | 5 |
| 2012 | 7 | 0 | 7 |
| 2013 | 4 | 1 | 5 |
| 2014 | 7 | 1 | 8 |
| 2015 | 8 | 2 | 10 |
| 2016 | 4 | 3 | 7 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 2 | 3 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 1 | 3 |
| 2021 | 6 | 1 | 7 |
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Below are the most recent publications written about "Retinal Pigment Epithelium" by people in Profiles.
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Rohrer B, Parsons N, Annamalai B, Nicholson C, Obert E, Jones BW, Dick AD. Peptide-based immunotherapy against oxidized elastin ameliorates pathology in mouse model of smoke-induced ocular injury. Exp Eye Res. 2021 11; 212:108755.
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Rohrer B, Biswal MR, Obert E, Dang Y, Su Y, Zuo X, Fogelgren B, Kondkar AA, Lobo GP, Lipschutz JH. Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function. Int J Mol Sci. 2021 May 11; 22(10).
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Annamalai B, Parsons N, Nicholson C, Joseph K, Coughlin B, Yang X, Jones BW, Tomlinson S, Rohrer B. Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration. Exp Eye Res. 2021 06; 207:108583.
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Annamalai B, Parsons N, Nicholson C, Obert E, Jones B, Rohrer B. Subretinal Rather Than Intravitreal Adeno-Associated Virus-Mediated Delivery of a Complement Alternative Pathway Inhibitor Is Effective in a Mouse Model of RPE Damage. Invest Ophthalmol Vis Sci. 2021 04 01; 62(4):11.
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Ishii M, Beeson G, Beeson C, Rohrer B. Mitochondrial C3a Receptor Activation in Oxidatively Stressed Epithelial Cells Reduces Mitochondrial Respiration and Metabolism. Front Immunol. 2021; 12:628062.
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Boyer NP, Thompson DA, Koutalos Y. Relative Contributions of All-Trans and 11-Cis Retinal to Formation of Lipofuscin and A2E Accumulating in Mouse Retinal Pigment Epithelium. Invest Ophthalmol Vis Sci. 2021 02 01; 62(2):1.
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Ishii M, Beeson G, Beeson C, Rohrer B. Isolation of Mitochondria from Retinal Pigment Epithelial Cell Cultures and an Application of High-Resolution Respirometric Assay (XFe96 Seahorse Assay). Methods Mol Biol. 2021; 2277:423-431.
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Schnabolk G, Obert E, Banda NK, Rohrer B. Systemic Inflammation by Collagen-Induced Arthritis Affects the Progression of Age-Related Macular Degeneration Differently in Two Mouse Models of the Disease. Invest Ophthalmol Vis Sci. 2020 12 01; 61(14):11.
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Nicholson C, Ishii M, Annamalai B, Chandler K, Chwa M, Kenney MC, Shah N, Rohrer B. J or H mtDNA haplogroups in retinal pigment epithelial cells: Effects on cell physiology, cargo in extracellular vesicles, and differential uptake of such vesicles by naïve recipient cells. Biochim Biophys Acta Gen Subj. 2021 04; 1865(4):129798.
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Fu D, Yu JY, Connell AR, Hookham MB, McLeese RH, Lyons TJ. Effects of Modified Low-Density Lipoproteins and Fenofibrate on an Outer Blood-Retina Barrier Model: Implications for Diabetic Retinopathy. J Ocul Pharmacol Ther. 2020 12; 36(10):754-764.