"Retinal Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Descriptor ID |
D012162
|
| MeSH Number(s) |
C11.768.585
|
| Concept/Terms |
Retinal Degeneration- Retinal Degeneration
- Degeneration, Retinal
- Degenerations, Retinal
- Retinal Degenerations
|
Below are MeSH descriptors whose meaning is more general than "Retinal Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Retinal Degeneration".
This graph shows the total number of publications written about "Retinal Degeneration" by people in this website by year, and whether "Retinal Degeneration" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 3 | 0 | 3 |
| 2007 | 4 | 1 | 5 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 3 | 1 | 4 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 4 | 0 | 4 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Retinal Degeneration" by people in Profiles.
-
The role of motor proteins in photoreceptor protein transport and visual function. Ophthalmic Genet. 2022 06; 43(3):285-300.
-
Evidence for ceramide induced cytotoxicity in retinal ganglion cells. Exp Eye Res. 2021 10; 211:108762.
-
Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function. Int J Mol Sci. 2021 May 11; 22(10).
-
Newly Identified Chemicals Preserve Mitochondrial Capacity and Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models. J Ocul Pharmacol Ther. 2021 Jul-Aug; 37(6):367-378.
-
Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration. Exp Eye Res. 2021 06; 207:108583.
-
Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice. PLoS Genet. 2019 05; 15(5):e1008130.
-
All-trans retinal levels and formation of lipofuscin precursors after bleaching in rod photoreceptors from wild type and Abca4-/- mice. Exp Eye Res. 2017 02; 155:121-127.
-
Suppression of Acid Sphingomyelinase Protects the Retina from Ischemic Injury. Invest Ophthalmol Vis Sci. 2016 08 01; 57(10):4476-84.
-
Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration. PLoS One. 2016; 11(3):e0151806.
-
Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015 May; 56(5):3361-70.