"Orexins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Neuropeptide hormones that play a role in regulating a variety of behavioral and physiological processes in response to motivational stimuli.
| Descriptor ID |
D000068797
|
| MeSH Number(s) |
D12.644.400.360 D12.776.631.650.363
|
| Concept/Terms |
Orexin-B- Orexin-B
- Orexin B
- Hypocretin-2
- Hypocretin 2
Orexin-A- Orexin-A
- Orexin A
- Hypocretin-1
- Hypocretin 1
|
Below are MeSH descriptors whose meaning is more general than "Orexins".
Below are MeSH descriptors whose meaning is more specific than "Orexins".
This graph shows the total number of publications written about "Orexins" by people in this website by year, and whether "Orexins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2013 | 0 | 2 | 2 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Orexins" by people in Profiles.
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Intranasal insulin and orexins to treat age-related cognitive decline. Physiol Behav. 2021 05 15; 234:113370.
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Non-Opioid Treatments for Opioid Use Disorder: Rationales and Data to Date. Drugs. 2020 Oct; 80(15):1509-1524.
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Contribution of Dynorphin and Orexin Neuropeptide Systems to the Motivational Effects of Alcohol. Handb Exp Pharmacol. 2018; 248:473-503.
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Rewiring brain circuits to block cataplexy in murine models of narcolepsy. Curr Opin Neurobiol. 2017 06; 44:110-115.
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Upregulation of orexin/hypocretin expression in aged rats: Effects on feeding latency and neurotransmission in the insular cortex. Neuroscience. 2017 05 14; 350:124-132.
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Activation of orexin/hypocretin neurons is associated with individual differences in cued fear extinction. Physiol Behav. 2017 Sep 01; 178:93-102.
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Orexin gene transfer into the amygdala suppresses both spontaneous and emotion-induced cataplexy in orexin-knockout mice. Eur J Neurosci. 2016 Mar; 43(5):681-8.
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Food for thought: the role of appetitive peptides in age-related cognitive decline. Ageing Res Rev. 2013 Jun; 12(3):764-76.
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Effects of orexin gene transfer in the dorsolateral pons in orexin knockout mice. Sleep. 2013 Jan 01; 36(1):31-40.
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Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual Orexin inhibitor Suvorexant (MK-4305). J Am Chem Soc. 2011 Jun 01; 133(21):8362-71.