Pituitary Adenylate Cyclase-Activating Polypeptide
"Pituitary Adenylate Cyclase-Activating Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake.
| Descriptor ID |
D051219
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| MeSH Number(s) |
D12.644.276.860.887 D12.644.400.625 D12.776.467.860.887 D12.776.631.600.887 D12.776.631.650.625 D23.529.850.887
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pituitary Adenylate Cyclase-Activating Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Pituitary Adenylate Cyclase-Activating Polypeptide".
This graph shows the total number of publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in this website by year, and whether "Pituitary Adenylate Cyclase-Activating Polypeptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in Profiles.
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cAMP-induced decrease in cell-surface laminin receptor and cellular prion protein attenuates amyloid-? uptake and amyloid-?-induced neuronal cell death. FEBS Lett. 2022 11; 596(22):2914-2927.
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PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus. Proc Natl Acad Sci U S A. 2014 Feb 25; 111(8):3158-63.
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A secretin i.v. infusion activates gene expression in the central amygdala of rats. Neuroscience. 2003; 118(4):881-8.
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Pituitary adenylate cyclase activating peptide (PACAP) in the enteropancreatic innervation. Anat Rec. 2001 01 01; 262(1):91-100.