"Superoxide Dismutase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.
| Descriptor ID |
D000072105
|
| MeSH Number(s) |
D08.811.682.881.500
|
| Concept/Terms |
Superoxide Dismutase-1- Superoxide Dismutase-1
- Cuprozinc Superoxide Dismutase
- Superoxide Dismutase, Cuprozinc
- Superoxide Dismutase 1
- Cu-Zn Superoxide Dismutase
- Cu Zn Superoxide Dismutase
- Superoxide Dismutase, Cu-Zn
- SOD-1 Protein
- SOD 1 Protein
- SOD1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Superoxide Dismutase-1".
Below are MeSH descriptors whose meaning is more specific than "Superoxide Dismutase-1".
This graph shows the total number of publications written about "Superoxide Dismutase-1" by people in this website by year, and whether "Superoxide Dismutase-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 3 | 3 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 2 | 4 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Superoxide Dismutase-1" by people in Profiles.
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Chitooligosaccharide prevents vascular endothelial cell apoptosis by attenuation of endoplasmic reticulum stress via suppression of oxidative stress through Nrf2-SOD1 up-regulation. Pharm Biol. 2022 Dec; 60(1):2155-2166.
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NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons. FASEB J. 2022 04; 36(4):e22262.
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Effects of Aging on Cardiac Oxidative Stress and Transcriptional Changes in Pathways of Reactive Oxygen Species Generation and Clearance. J Am Heart Assoc. 2021 08 17; 10(16):e019948.
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Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model. FASEB J. 2021 02; 35(2):e21343.
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Direct Observation of ?-Barrel Intermediates in the Self-Assembly of Toxic SOD128-38 and Absence in Nontoxic Glycine Mutants. J Chem Inf Model. 2021 02 22; 61(2):966-975.
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Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function. Am J Physiol Cell Physiol. 2020 11 01; 319(5):C933-C944.
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Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice. Pharmacol Res Perspect. 2020 08; 8(4):e00636.
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FABP7 upregulation induces a neurotoxic phenotype in astrocytes. Glia. 2020 12; 68(12):2693-2704.
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Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models. Exp Neurol. 2020 05; 327:113219.
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Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1. FASEB J. 2019 06; 33(6):7084-7091.