"NF-E2-Related Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
| Descriptor ID |
D051267
|
| MeSH Number(s) |
D12.776.260.108.737 D12.776.930.127.737
|
| Concept/Terms |
NF-E2-Related Factor 2- NF-E2-Related Factor 2
- NF E2 Related Factor 2
- Nuclear Factor E2-Related Factor 2
- Nuclear Factor E2 Related Factor 2
- Nfe2l2 Protein
- Nuclear Factor (Erythroid-Derived 2)-Like 2 Protein
|
Below are MeSH descriptors whose meaning is more general than "NF-E2-Related Factor 2".
Below are MeSH descriptors whose meaning is more specific than "NF-E2-Related Factor 2".
This graph shows the total number of publications written about "NF-E2-Related Factor 2" by people in this website by year, and whether "NF-E2-Related Factor 2" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 |
| 2005 | 1 | 2 | 3 |
| 2006 | 2 | 1 | 3 |
| 2007 | 3 | 0 | 3 |
| 2008 | 2 | 0 | 2 |
| 2009 | 6 | 0 | 6 |
| 2010 | 2 | 0 | 2 |
| 2011 | 4 | 0 | 4 |
| 2012 | 4 | 0 | 4 |
| 2013 | 3 | 0 | 3 |
| 2014 | 5 | 0 | 5 |
| 2015 | 3 | 0 | 3 |
| 2016 | 4 | 0 | 4 |
| 2017 | 1 | 0 | 1 |
| 2018 | 6 | 1 | 7 |
| 2019 | 2 | 3 | 5 |
| 2020 | 3 | 1 | 4 |
| 2021 | 2 | 2 | 4 |
| 2022 | 4 | 1 | 5 |
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Below are the most recent publications written about "NF-E2-Related Factor 2" by people in Profiles.
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Chitooligosaccharide prevents vascular endothelial cell apoptosis by attenuation of endoplasmic reticulum stress via suppression of oxidative stress through Nrf2-SOD1 up-regulation. Pharm Biol. 2022 Dec; 60(1):2155-2166.
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Nrf2-Mediated Dichotomy in the Vascular System: Mechanistic and Therapeutic Perspective. Cells. 2022 09 28; 11(19).
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Platanosides, a Potential Botanical Drug Combination, Decrease Liver Injury Caused by Acetaminophen Overdose in Mice. J Nat Prod. 2022 07 22; 85(7):1779-1788.
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The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2. Cells. 2022 06 14; 11(12).
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BACH1-Hemoxygenase-1 axis regulates cellular energetics and survival following sepsis. Free Radic Biol Med. 2022 08 01; 188:134-145.
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Identification of a potent Nrf2 displacement activator among aspirin-containing prodrugs. Neurochem Int. 2021 10; 149:105148.
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Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair. Free Radic Biol Med. 2021 06; 169:238-247.
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Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model. FASEB J. 2021 02; 35(2):e21343.
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Glutathione S-Transferase P Influences Redox Homeostasis and Response to Drugs that Induce the Unfolded Protein Response in Zebrafish. J Pharmacol Exp Ther. 2021 04; 377(1):121-132.
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Autophagy Inhibition Enables Nrf2 to Exaggerate the Progression of Diabetic Cardiomyopathy in Mice. Diabetes. 2020 12; 69(12):2720-2734.