"NAD" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
| Descriptor ID |
D009243
|
| MeSH Number(s) |
D03.633.100.759.646.138.694 D08.211.589 D13.695.667.138.694 D13.695.827.068.694
|
| Concept/Terms |
NAD- NAD
- Dihydronicotinamide Adenine Dinucleotide
- Adenine Dinucleotide, Dihydronicotinamide
- Dinucleotide, Dihydronicotinamide Adenine
- Diphosphopyridine Nucleotide
- Nucleotide, Diphosphopyridine
- Nadide
- Nicotinamide-Adenine Dinucleotide
- Dinucleotide, Nicotinamide-Adenine
- Nicotinamide Adenine Dinucleotide
- Coenzyme I
- DPN
|
Below are MeSH descriptors whose meaning is more general than "NAD".
Below are MeSH descriptors whose meaning is more specific than "NAD".
This graph shows the total number of publications written about "NAD" by people in this website by year, and whether "NAD" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 1 | 3 |
| 2011 | 1 | 0 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 3 | 2 | 5 |
| 2022 | 2 | 2 | 4 |
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Below are the most recent publications written about "NAD" by people in Profiles.
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Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science. 2022 09 30; 377(6614):eadc8969.
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SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein. PLoS Pathog. 2022 09; 18(9):e1010811.
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Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells. Biomed Pharmacother. 2022 Jun; 150:112928.
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Fast Determination of Mitochondrial Metabolism and Respiratory Complex Activity in Permeabilized and Intact Cells. Methods Mol Biol. 2022; 2497:1-10.
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Cautionary Tale of Using Tris(alkyl)phosphine Reducing Agents with NAD+-Dependent Enzymes. Biochemistry. 2020 09 15; 59(36):3285-3289.
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CD38: T Cell Immuno-Metabolic Modulator. Cells. 2020 07 17; 9(7).
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Quinolinate as a Marker for Kynurenine Metabolite Formation and the Unresolved Question of NAD+ Synthesis During Inflammation and Infection. Front Immunol. 2020; 11:31.
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CD38: Modulating Histone Methyltransferase EZH2 Activity in SLE. Trends Immunol. 2020 03; 41(3):187-189.
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Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models. Exp Neurol. 2020 05; 327:113219.
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CD38-NAD+-Sirt1 axis in T cell immunotherapy. Aging (Albany NY). 2019 10 23; 11(20):8743-8744.