Protein Domains

"Protein Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Discrete protein structural units that may fold independently of the rest of the protein and have their own functions.

Descriptor ID	D000072417
MeSH Number(s)	G02.111.570.820.709.275.750 G02.111.570.820.709.610.500
Concept/Terms	Protein Domains Protein Domains Peptide Domain Domain, Peptide Domains, Peptide Peptide Domains Protein Domain Domain, Protein Domains, Protein

Below are MeSH descriptors whose meaning is more general than "Protein Domains".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.820]
Protein Conformation [G02.111.570.820.709]
Protein Structural Elements [G02.111.570.820.709.275]
Protein Domains [G02.111.570.820.709.275.750]
Protein Structure, Tertiary [G02.111.570.820.709.610]
Protein Domains [G02.111.570.820.709.610.500]

Below are MeSH descriptors whose meaning is related to "Protein Domains".

Below are MeSH descriptors whose meaning is more specific than "Protein Domains".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein Domains" by people in this website by year, and whether "Protein Domains" was a major or minor topic of these publications.

Bar chart showing 45 publications over 8 distinct years, with a maximum of 11 publications in 2017

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2015	1	1
2016	8	8
2017	11	11
2018	4	4
2019	4	4
2020	10	10
2021	5	5
2022	2	2

Below are the most recent publications written about "Protein Domains" by people in Profiles.

Nayak D, Wasmuth EV, Olsen SK. Clearing the air: Uniquely engaging furin as an approach to cystic fibrosis therapy. Cell Chem Biol. 2022 06 16; 29(6):927-929.

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Palethorpe S, Milton ME, Pesci EC, Cavanagh J. Structure of the Acinetobacter baumannii PmrA receiver domain and insights into clinical mutants affecting DNA binding and promoting colistin resistance. J Biochem. 2022 Jan 07; 170(6):787-800.

View in: PubMed
Weissman JD, Singh AK, Devaiah BN, Schuck P, LaRue RC, Singer DS. The intrinsic kinase activity of BRD4 spans its BD2-B-BID domains. J Biol Chem. 2021 11; 297(5):101326.

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Singh A, Izac JR, Schuler EJA, Patel DT, Davies C, Marconi RT. High-resolution crystal structure of the Borreliella burgdorferi PlzA protein in complex with c-di-GMP: new insights into the interaction of c-di-GMP with the novel xPilZ domain. Pathog Dis. 2021 06 29; 79(5).

View in: PubMed
Frankel BM, Cachia D, Patel SJ, Das A. Analysis of the P53N a Novel Protein Encoded on Chromosome 22q12.1-12.3 in Glioblastomas and Ependymomas Specimens. J Mol Neurosci. 2021 Aug; 71(8):1714-1722.

View in: PubMed
Ghidoni A, Elliott PM, Syrris P, Calkins H, James CA, Judge DP, Murray B, Barc J, Probst V, Schott JJ, Song JP, Hauer RNW, Hoorntje ET, van Tintelen JP, Schulze-Bahr E, Hamilton RM, Mittal K, Semsarian C, Behr ER, Ackerman MJ, Basso C, Parati G, Gentilini D, Kotta MC, Mayosi BM, Schwartz PJ, Crotti L. Cadherin 2-Related Arrhythmogenic Cardiomyopathy: Prevalence and Clinical Features. Circ Genom Precis Med. 2021 04; 14(2):e003097.

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Zhang X, Ameer FS, Azhar G, Wei JY. Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function. Int J Mol Sci. 2021 Jan 06; 22(2).

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Lobb DC, Doviak H, Brower GL, Romito E, O'Neill JW, Smith S, Shuman JA, Freels PD, Zellars KN, Freeburg LA, Khakoo AY, Lee T, Spinale FG. Targeted Injection of a Truncated Form of Tissue Inhibitor of Metalloproteinase 3 Alters Post-Myocardial Infarction Remodeling. J Pharmacol Exp Ther. 2020 11; 375(2):296-307.

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Patel SM, Smith TG, Morton M, Stiers KM, Seravalli J, Mayclin SJ, Edwards TE, Tanner JJ, Becker DF. Cautionary Tale of Using Tris(alkyl)phosphine Reducing Agents with NAD+-Dependent Enzymes. Biochemistry. 2020 09 15; 59(36):3285-3289.

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Medina E, Villalobos P, Hamilton GL, Komives EA, Sanabria H, Ramírez-Sarmiento CA, Babul J. Intrinsically Disordered Regions of the DNA-Binding Domain of Human FoxP1 Facilitate Domain Swapping. J Mol Biol. 2020 09 04; 432(19):5411-5429.

View in: PubMed

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