"Procaine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
| Descriptor ID |
D011343
|
| MeSH Number(s) |
D02.241.223.100.050.500.906 D02.455.426.559.389.127.020.937.906
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Procaine".
Below are MeSH descriptors whose meaning is more specific than "Procaine".
This graph shows the total number of publications written about "Procaine" by people in this website by year, and whether "Procaine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 3 | 3 |
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Below are the most recent publications written about "Procaine" by people in Profiles.
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Churchill L, Kalivas PW. The involvement of the mediodorsal nucleus of the thalamus and the midbrain extrapyramidal area in locomotion elicited from the ventral pallidum. Behav Brain Res. 1999 Oct; 104(1-2):63-71.
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Hamner MB, Lorberbaum JP, George MS. Potential role of the anterior cingulate cortex in PTSD: review and hypothesis. Depress Anxiety. 1999; 9(1):1-14.
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Cornish JL, Duffy P, Kalivas PW. A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior. Neuroscience. 1999; 93(4):1359-67.
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Middaugh LD, McGroarty KK, Groseclose CH, Adinoff B. Cocaine discrimination: relationship to local anesthetics and monoamine uptake inhibitors in C57BL/6 mice. Psychopharmacology (Berl). 1998 Mar; 136(1):44-9.
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Woodward JJ, Compton DM, Balster RL, Martin BR. In vitro and in vivo effects of cocaine and selected local anesthetics on the dopamine transporter. Eur J Pharmacol. 1995 Apr 13; 277(1):7-13.
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Kling MA, Gardner DL, Calogero AE, Coppola R, Trettau J, Kellner CH, Lefter L, Hart MJ, Cowdry RW, Post RM, et al. Effects of local anesthetics on experiential, physiologic and endocrine measures in healthy humans and on rat hypothalamic corticotropin-releasing hormone release in vitro: clinical and psychobiologic implications. J Pharmacol Exp Ther. 1994 Mar; 268(3):1548-64.
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Silva P, Epstein FH, Karnaky KJ, Reichlin S, Forrest JN. Neuropeptide Y inhibits chloride secretion in the shark rectal gland. Am J Physiol. 1993 Aug; 265(2 Pt 2):R439-46.
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Kellner CH, Post RM, Putnam F, Cowdry R, Gardner D, Kling MA, Minichiello MD, Trettau JR, Coppola R. Intravenous procaine as a probe of limbic system activity in psychiatric patients and normal controls. Biol Psychiatry. 1987 Sep; 22(9):1107-26.
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Kling MA, Kellner CH, Post RM, Cowdry RW, Gardner DL, Coppola R, Putnam FW, Gold PW. Neuroendocrine effects of limbic activation by electrical, spontaneous, and pharmacological modes: relevance to the pathophysiology of affective dysregulation in psychiatric disorders. Prog Neuropsychopharmacol Biol Psychiatry. 1987; 11(4):459-81.