Nicotinamide-Nucleotide Adenylyltransferase
"Nicotinamide-Nucleotide Adenylyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals.
| Descriptor ID |
D009612
|
| MeSH Number(s) |
D08.811.913.696.445.600 D12.776.157.687.499 D12.776.660.720.499
|
| Concept/Terms |
Nicotinamide-Nucleotide Adenylyltransferase- Nicotinamide-Nucleotide Adenylyltransferase
- Adenylyltransferase, Nicotinamide-Nucleotide
- Nicotinamide Nucleotide Adenylyltransferase
- NMN Adenylyltransferase
- Adenylyltransferase, NMN
- Nicotinamide Mononucleotide Adenylyltransferase
- Adenylyltransferase, Nicotinamide Mononucleotide
- Mononucleotide Adenylyltransferase, Nicotinamide
- ATP-NMN Adenylyltransferase
- ATP NMN Adenylyltransferase
- Adenylyltransferase, ATP-NMN
- NAD Pyrophosphorylase
- Pyrophosphorylase, NAD
|
Below are MeSH descriptors whose meaning is more general than "Nicotinamide-Nucleotide Adenylyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Nicotinamide-Nucleotide Adenylyltransferase".
This graph shows the total number of publications written about "Nicotinamide-Nucleotide Adenylyltransferase" by people in this website by year, and whether "Nicotinamide-Nucleotide Adenylyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nicotinamide-Nucleotide Adenylyltransferase" by people in Profiles.
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Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models. Exp Neurol. 2020 05; 327:113219.
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Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. Ann Rheum Dis. 2016 Nov; 75(11):2007-2013.