DNA-Activated Protein Kinase
"DNA-Activated Protein Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine-threonine protein kinase that, when activated by DNA, phosphorylates several DNA-binding protein substrates including the TUMOR SUPPRESSOR PROTEIN P53 and a variety of TRANSCRIPTION FACTORS.
| Descriptor ID |
D051747
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.250 D12.776.157.687.438 D12.776.660.720.438
|
| Concept/Terms |
DNA-Activated Protein Kinase- DNA-Activated Protein Kinase
- DNA Activated Protein Kinase
- Kinase, DNA-Activated Protein
- Protein Kinase, DNA-Activated
- DNA-Dependent Protein Serine-Threonine Kinase
- DNA Dependent Protein Serine Threonine Kinase
- DNA-Dependent Protein Kinase
- DNA Dependent Protein Kinase
- Kinase, DNA-Dependent Protein
- Protein Kinase, DNA-Dependent
|
Below are MeSH descriptors whose meaning is more general than "DNA-Activated Protein Kinase".
Below are MeSH descriptors whose meaning is more specific than "DNA-Activated Protein Kinase".
This graph shows the total number of publications written about "DNA-Activated Protein Kinase" by people in this website by year, and whether "DNA-Activated Protein Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA-Activated Protein Kinase" by people in Profiles.
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Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells. Mol Cancer Ther. 2002 Oct; 1(12):1089-95.
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Glutathione conjugate interactions with DNA-dependent protein kinase. J Pharmacol Exp Ther. 1999 Sep; 290(3):1101-6.
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Increased expression of DNA-dependent protein kinase confers resistance to adriamycin. Biochim Biophys Acta. 1998 Jul 23; 1381(2):131-8.
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Coordinate changes in expression of protective genes in drug-resistant cells. Chem Biol Interact. 1998 Apr 24; 111-112:199-211.