Receptor, Platelet-Derived Growth Factor alpha
"Receptor, Platelet-Derived Growth Factor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A PDGF receptor that binds specifically to both PDGF-A chains and PDGF-B chains. It contains a protein-tyrosine kinase activity that is involved in SIGNAL TRANSDUCTION.
| Descriptor ID |
D020796
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.900.500 D12.776.543.750.630.625.300 D12.776.543.750.750.400.630.300
|
| Concept/Terms |
Receptor, Platelet-Derived Growth Factor alpha- Receptor, Platelet-Derived Growth Factor alpha
- Platelet-Derived Growth Factor alpha Receptor
- Platelet Derived Growth Factor alpha Receptor
- Antigens, CD140a
- PDGFRalpha
- PDGF-R-alpha
- Receptor, PDGF alpha
- CD140a Antigen
- Antigen, CD140a
- PDGFR2
- PDGF alpha Receptor
- CD140a Antigens
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Platelet-Derived Growth Factor alpha".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Transferases [D08.811.913]
- Phosphotransferases [D08.811.913.696]
- Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
- Protein Kinases [D08.811.913.696.620.682]
- Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
- Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
- Receptors, Platelet-Derived Growth Factor [D08.811.913.696.620.682.725.400.900]
- Receptor, Platelet-Derived Growth Factor alpha [D08.811.913.696.620.682.725.400.900.500]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
- Receptors, Platelet-Derived Growth Factor [D12.776.543.750.630.625]
- Receptor, Platelet-Derived Growth Factor alpha [D12.776.543.750.630.625.300]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Platelet-Derived Growth Factor [D12.776.543.750.750.400.630]
- Receptor, Platelet-Derived Growth Factor alpha [D12.776.543.750.750.400.630.300]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Platelet-Derived Growth Factor alpha".
This graph shows the total number of publications written about "Receptor, Platelet-Derived Growth Factor alpha" by people in this website by year, and whether "Receptor, Platelet-Derived Growth Factor alpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor, Platelet-Derived Growth Factor alpha" by people in Profiles.
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Hammer AM, Sizemore GM, Shukla VC, Avendano A, Sizemore ST, Chang JJ, Kladney RD, Cuitiño MC, Thies KA, Verfurth Q, Chakravarti A, Yee LD, Leone G, Song JW, Ghadiali SN, Ostrowski MC. Stromal PDGFR-a Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth. Neoplasia. 2017 Jun; 19(6):496-508.
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Eckert MA, Lwin TM, Chang AT, Kim J, Danis E, Ohno-Machado L, Yang J. Twist1-induced invadopodia formation promotes tumor metastasis. Cancer Cell. 2011 Mar 08; 19(3):372-86.
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Russell MR, Jamieson WL, Dolloff NG, Fatatis A. The alpha-receptor for platelet-derived growth factor as a target for antibody-mediated inhibition of skeletal metastases from prostate cancer cells. Oncogene. 2009 Jan 22; 28(3):412-21.
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McCabe CD, Spyropoulos DD, Martin D, Moreno CS. Genome-wide analysis of the homeobox C6 transcriptional network in prostate cancer. Cancer Res. 2008 Mar 15; 68(6):1988-96.
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Kang J, Gu Y, Li P, Johnson BL, Sucov HM, Thomas PS. PDGF-A as an epicardial mitogen during heart development. Dev Dyn. 2008 Mar; 237(3):692-701.
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Bland RD, Xu L, Ertsey R, Rabinovitch M, Albertine KH, Wynn KA, Kumar VH, Ryan RM, Swartz DD, Csiszar K, Fong KS. Dysregulation of pulmonary elastin synthesis and assembly in preterm lambs with chronic lung disease. Am J Physiol Lung Cell Mol Physiol. 2007 Jun; 292(6):L1370-84.
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Dolloff NG, Russell MR, Loizos N, Fatatis A. Human bone marrow activates the Akt pathway in metastatic prostate cells through transactivation of the alpha-platelet-derived growth factor receptor. Cancer Res. 2007 Jan 15; 67(2):555-62.
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Gudz TI, Komuro H, Macklin WB. Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex. J Neurosci. 2006 Mar 01; 26(9):2458-66.
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Dolloff NG, Shulby SS, Nelson AV, Stearns ME, Johannes GJ, Thomas JD, Meucci O, Fatatis A. Bone-metastatic potential of human prostate cancer cells correlates with Akt/PKB activation by alpha platelet-derived growth factor receptor. Oncogene. 2005 Oct 13; 24(45):6848-54.
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Paintlia MK, Paintlia AS, Barbosa E, Singh I, Singh AK. N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain. J Neurosci Res. 2004 Nov 01; 78(3):347-61.