Phosphotransferases (Alcohol Group Acceptor)
"Phosphotransferases (Alcohol Group Acceptor)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of enzymes that transfers a phosphate group onto an alcohol group acceptor. EC 2.7.1.
| Descriptor ID |
D017853
|
| MeSH Number(s) |
D08.811.913.696.620
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phosphotransferases (Alcohol Group Acceptor)".
Below are MeSH descriptors whose meaning is more specific than "Phosphotransferases (Alcohol Group Acceptor)".
This graph shows the total number of publications written about "Phosphotransferases (Alcohol Group Acceptor)" by people in this website by year, and whether "Phosphotransferases (Alcohol Group Acceptor)" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 3 | 0 | 3 |
| 1996 | 3 | 0 | 3 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 3 | 2 | 5 |
| 2004 | 2 | 0 | 2 |
| 2005 | 6 | 2 | 8 |
| 2006 | 4 | 1 | 5 |
| 2007 | 3 | 2 | 5 |
| 2008 | 3 | 2 | 5 |
| 2009 | 2 | 0 | 2 |
| 2010 | 6 | 2 | 8 |
| 2011 | 9 | 0 | 9 |
| 2012 | 9 | 0 | 9 |
| 2013 | 5 | 2 | 7 |
| 2014 | 3 | 1 | 4 |
| 2015 | 5 | 2 | 7 |
| 2016 | 2 | 0 | 2 |
| 2017 | 4 | 1 | 5 |
| 2018 | 6 | 3 | 9 |
| 2019 | 3 | 0 | 3 |
| 2020 | 2 | 0 | 2 |
| 2021 | 5 | 0 | 5 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphotransferases (Alcohol Group Acceptor)" by people in Profiles.
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Upregulation of sphingosine kinase 1 in response to doxorubicin generates an angiogenic response via stabilization of Snail. FASEB J. 2023 03; 37(3):e22787.
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Phase I study of opaganib, an oral sphingosine kinase 2-specific inhibitor, in relapsed and/or refractory multiple myeloma. Ann Hematol. 2023 Feb; 102(2):369-383.
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1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase. J Lipid Res. 2022 01; 63(1):100154.
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Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer. PLoS One. 2021; 16(5):e0252311.
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Ceramide kinase regulates TNF-a-induced immune responses in human monocytic cells. Sci Rep. 2021 04 15; 11(1):8259.
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Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation. FASEB J. 2021 02; 35(2):e21284.
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Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides. Cell Death Dis. 2021 01 04; 12(1):27.
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Transcriptional Regulation of Sphingosine Kinase 1. Cells. 2020 11 08; 9(11).
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Analysis of selective target engagement by small-molecule sphingosine kinase inhibitors using the Cellular Thermal Shift Assay (CETSA). Cancer Biol Ther. 2020 09 01; 21(9):841-852.
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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity. Cell Rep. 2019 08 13; 28(7):1879-1893.e7.