Phosphofructokinase-1, Muscle Type
"Phosphofructokinase-1, Muscle Type" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.
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Below are the most recent publications written about "Phosphofructokinase-1, Muscle Type" by people in Profiles.
A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. Cancer Epidemiol Biomarkers Prev. 2014 Apr; 23(4):658-69.