"Adherens Junctions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Anchoring points where the CYTOSKELETON of neighboring cells are connected to each other. They are composed of specialized areas of the plasma membrane where bundles of the ACTIN CYTOSKELETON attach to the membrane through the transmembrane linkers, CADHERINS, which in turn attach through their extracellular domains to cadherins in the neighboring cell membranes. In sheets of cells, they form into adhesion belts (zonula adherens) that go all the way around a cell.
| Descriptor ID |
D022005
|
| MeSH Number(s) |
A11.284.149.165.420.020
|
| Concept/Terms |
Adherens Junctions- Adherens Junctions
- Adherens Junction
- Junction, Adherens
- Junctions, Adherens
|
Below are MeSH descriptors whose meaning is more general than "Adherens Junctions".
Below are MeSH descriptors whose meaning is more specific than "Adherens Junctions".
This graph shows the total number of publications written about "Adherens Junctions" by people in this website by year, and whether "Adherens Junctions" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Adherens Junctions" by people in Profiles.
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A Simple Method to Test Mechanical Strain on Epithelial Cell Monolayers Using a 3D-Printed Stretcher. Methods Mol Biol. 2021; 2367:235-247.
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Predominant Distribution of the RNAi Machinery at Apical Adherens Junctions in Colonic Epithelia Is Disrupted in Cancer. Int J Mol Sci. 2020 Apr 07; 21(7).
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Close encounters of the RNAi kind: the silencing life of the adherens junctions. Curr Opin Cell Biol. 2018 10; 54:30-36.
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Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling. J Cell Biol. 2017 10 02; 216(10):3073-3085.
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A central role for cadherin signaling in cancer. Exp Cell Res. 2017 09 01; 358(1):78-85.
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Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120?catenin activity. Nat Cell Biol. 2015 Sep; 17(9):1145-57.
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ZO-1 determines adherens and gap junction localization at intercalated disks. Am J Physiol Heart Circ Physiol. 2011 Feb; 300(2):H583-94.
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The Drosophila metastasis suppressor gene Nm23 homolog, awd, regulates epithelial integrity during oogenesis. Mol Cell Biol. 2009 Sep; 29(17):4679-90.
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Effects of pharmacologic inhibition of protein geranylgeranyltransferase type I on aqueous humor outflow through the trabecular meshwork. Invest Ophthalmol Vis Sci. 2008 Jun; 49(6):2464-71.
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Junctional adhesion molecule-A is critical for the formation of pseudocanaliculi and modulates E-cadherin expression in hepatic cells. J Biol Chem. 2007 Sep 21; 282(38):28137-48.