"Versicans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
HYALURONAN-containing proteoglycans found in the EXTRACELLULAR MATRIX of a variety of tissues and organs. Several versican isoforms exist due to multiple ALTERNATIVE SPLICING of the versican MESSENGER RNA.
| Descriptor ID |
D053675
|
| MeSH Number(s) |
D09.698.735.200.750 D12.776.395.650.750.687.800 D12.776.503.280.437.800 D12.776.860.300.885
|
| Concept/Terms |
Versicans- Versicans
- Versican
- Chondroitin Sulfate Proteoglycan Core Protein 2
|
Below are MeSH descriptors whose meaning is more general than "Versicans".
Below are MeSH descriptors whose meaning is more specific than "Versicans".
This graph shows the total number of publications written about "Versicans" by people in this website by year, and whether "Versicans" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Versicans" by people in Profiles.
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Expression of V3 Versican by Rat Arterial Smooth Muscle Cells Promotes Differentiated and Anti-inflammatory Phenotypes. J Biol Chem. 2015 Aug 28; 290(35):21629-41.
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Imbalanced expression of Vcan mRNA splice form proteins alters heart morphology and cellular protein profiles. PLoS One. 2014; 9(2):e89133.
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BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration. PLoS One. 2013; 8(10):e77593.
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Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves. J Mol Cell Cardiol. 2013 Jul; 60:50-9.
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Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. Mech Dev. 2013 Apr-May; 130(4-5):272-89.
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Maladaptive matrix remodeling and regional biomechanical dysfunction in a mouse model of aortic valve disease. Matrix Biol. 2012 Apr; 31(3):197-205.
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Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease. Dev Biol. 2011 Sep 01; 357(1):152-64.
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Versican G1 domain and V3 isoform overexpression results in increased chondrogenesis in the developing chick limb in ovo. Anat Rec (Hoboken). 2010 Oct; 293(10):1669-78.
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Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies. Matrix Biol. 2010 May; 29(4):304-16.
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Versican knock-down compromises chondrogenesis in the embryonic chick limb. Anat Rec (Hoboken). 2008 Jan; 291(1):19-27.