"Aggrecans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Large HYALURONAN-containing proteoglycans found in articular cartilage (CARTILAGE, ARTICULAR). They form into aggregates that provide tissues with the capacity to resist high compressive and tensile forces.
| Descriptor ID |
D053674
|
| MeSH Number(s) |
D09.698.735.200.500 D12.776.395.650.750.687.100 D12.776.503.280.437.100 D12.776.860.300.140
|
| Concept/Terms |
Aggrecans- Aggrecans
- Cartilage-Specific Proteoglycan Core Proteins
- Cartilage Specific Proteoglycan Core Proteins
- Aggrecan
|
Below are MeSH descriptors whose meaning is more general than "Aggrecans".
Below are MeSH descriptors whose meaning is more specific than "Aggrecans".
This graph shows the total number of publications written about "Aggrecans" by people in this website by year, and whether "Aggrecans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aggrecans" by people in Profiles.
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Adamts5-/- Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate With Ascending Aortic Anomalies. Arterioscler Thromb Vasc Biol. 2019 10; 39(10):2067-2081.
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Hydroxyapatite and calcified elastin induce osteoblast-like differentiation in rat aortic smooth muscle cells. Exp Cell Res. 2014 Apr 15; 323(1):198-208.
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Investigating the role of DNA damage in tobacco smoking-induced spine degeneration. Spine J. 2014 Mar 01; 14(3):416-23.
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Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb. Development. 2009 Aug; 136(16):2825-35.
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Limb bud mesenchyme cultured under tensile strain remodel collagen type I tubes to produce fibrillar collagen type II. Biorheology. 2009; 46(6):439-50.
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Versican expression during synovial joint morphogenesis. Int J Biol Sci. 2007 Sep 07; 3(6):380-4.
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Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts. Mech Ageing Dev. 2006 Aug; 127(8):660-9.
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Distinct spatial and temporal distributions of aggrecan and versican in the embryonic chick heart. Anat Rec. 1999 12 01; 256(4):366-80.
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Segmental expression of aggrecan in the non-segmented perinotochordal sheath underlies normal segmentation of the vertebral column. Mech Dev. 1998 Dec; 79(1-2):213-7.
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Immunohistochemical localization of keratan sulfate and chondroitin 4- and 6-sulfate proteoglycans in subregions of the tectorial and basilar membranes. Hear Res. 1994 Sep; 79(1-2):83-93.