"Tenascin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hexameric extracellular matrix glycoprotein transiently expressed in many developing organs and often re-expressed in tumors. It is present in the central and peripheral nervous systems as well as in smooth muscle and tendons. (From Kreis & Vale, Guidebook to the Extracellular Matrix and Adhesion Proteins, 1993, p93)
| Descriptor ID |
D019063
|
| MeSH Number(s) |
D12.776.860.300.850
|
| Concept/Terms |
Tenascin- Tenascin
- Hexabrachion
- Tenascin-C
- Tenascin C
- Cytotactin
|
Below are MeSH descriptors whose meaning is more general than "Tenascin".
Below are MeSH descriptors whose meaning is more specific than "Tenascin".
This graph shows the total number of publications written about "Tenascin" by people in this website by year, and whether "Tenascin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 2 | 3 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 1 | 3 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tenascin" by people in Profiles.
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Imaging the Alternatively Spliced D Domain of Tenascin C in a Preclinical Model of Inflammatory Bowel Disease. Mol Imaging Biol. 2023 Apr; 25(2):314-323.
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Tenascin-C drives persistence of organ fibrosis. Nat Commun. 2016 06 03; 7:11703.
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Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valves. Dev Biol. 2013 Feb 15; 374(2):345-56.
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Localized expression of tenascin in systemic sclerosis-associated pulmonary fibrosis and its regulation by insulin-like growth factor binding protein 3. Arthritis Rheum. 2012 Jan; 64(1):272-80.
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Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol. 2008 May; 294(5):L843-61.
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Opposing roles of two isoforms of the Prx1 homeobox gene in chondrogenesis. Dev Dyn. 2005 Jul; 233(3):811-21.
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Involvement of matrix metalloproteinases and tenascin-C in elastin calcification. Cardiovasc Pathol. 2004 May-Jun; 13(3):146-55.
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Endodermal growth factors promote endocardial precursor cell formation from precardiac mesoderm. Dev Biol. 2003 Nov 01; 263(1):35-49.
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FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration. J Cell Biol. 2003 Apr 28; 161(2):393-402.
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Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins. J Immunol. 2001 Jun 15; 166(12):7534-42.