"Interleukin-11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.
- Interleukin 11
- Adipogenesis Inhibitory Factor
- Factor, Adipogenesis Inhibitory
- Inhibitory Factor, Adipogenesis
Below are MeSH descriptors whose meaning is more general than "Interleukin-11".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-11".
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Below are the most recent publications written about "Interleukin-11" by people in Profiles.
Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. J Clin Invest. 2018 01 02; 128(1):402-414.
Secreted frizzled-related protein-1 inhibits RANKL-dependent osteoclast formation. J Bone Miner Res. 2004 Nov; 19(11):1873-81.
CD34 expression by murine hematopoietic stem cells. Developmental changes and kinetic alterations. Ann N Y Acad Sci. 2001 Jun; 938:139-45.
Reversible expression of CD34 by murine hematopoietic stem cells. Blood. 1999 Oct 15; 94(8):2548-54.
Negative regulation by interleukin-3 (IL-3) of mouse early B-cell progenitors and stem cells in culture: transduction of the negative signals by betac and betaIL-3 proteins of IL-3 receptor and absence of negative regulation by granulocyte-macrophage colony-stimulating factor. Blood. 1998 Aug 01; 92(3):901-7.
Development of natural killer cells from lymphohematopoietic progenitors of murine fetal liver. Stem Cells. 1998; 16 Suppl 1:193-8.
In vitro expansion of hematopoietic stem cells. Stem Cells. 1997; 15 Suppl 1:7-11; discussion 12.
Modulation of early B lymphopoiesis by interleukin-3. Exp Hematol. 1996 Aug; 24(10):1225-31.
Thrombopoietin, the ligand for the Mpl receptor, synergizes with steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice. Blood. 1996 Jun 01; 87(11):4544-51.
Negative regulation of early T lymphopoiesis by interleukin-3 and interleukin-1 alpha. Blood. 1995 Dec 15; 86(12):4527-31.