"Interleukin-11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECURSOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.
Descriptor ID |
D017370
|
MeSH Number(s) |
D12.644.276.374.465.511 D12.776.467.374.465.511 D23.529.374.465.511
|
Concept/Terms |
Interleukin-11- Interleukin-11
- Interleukin 11
- IL-11
- IL11
- Adipogenesis Inhibitory Factor
- Factor, Adipogenesis Inhibitory
- Inhibitory Factor, Adipogenesis
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-11".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-11".
This graph shows the total number of publications written about "Interleukin-11" by people in this website by year, and whether "Interleukin-11" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1996 | 0 | 2 | 2 |
1997 | 0 | 1 | 1 |
1998 | 0 | 2 | 2 |
2001 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-11" by people in Profiles.
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Ollila S, Domènech-Moreno E, Laajanen K, Wong IP, Tripathi S, Pentinmikko N, Gao Y, Yan Y, Niemelä EH, Wang TC, Viollet B, Leone G, Katajisto P, Vaahtomeri K, Mäkelä TP. Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. J Clin Invest. 2018 01 02; 128(1):402-414.
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Häusler KD, Horwood NJ, Chuman Y, Fisher JL, Ellis J, Martin TJ, Rubin JS, Gillespie MT. Secreted frizzled-related protein-1 inhibits RANKL-dependent osteoclast formation. J Bone Miner Res. 2004 Nov; 19(11):1873-81.
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Ogawa M, Tajima F, Ito T, Sato T, Laver JH, Deguchi T. CD34 expression by murine hematopoietic stem cells. Developmental changes and kinetic alterations. Ann N Y Acad Sci. 2001 Jun; 938:139-45.
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Matsunaga T, Hirayama F, Yonemura Y, Murray R, Ogawa M. Negative regulation by interleukin-3 (IL-3) of mouse early B-cell progenitors and stem cells in culture: transduction of the negative signals by betac and betaIL-3 proteins of IL-3 receptor and absence of negative regulation by granulocyte-macrophage colony-stimulating factor. Blood. 1998 Aug 01; 92(3):901-7.
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Aiba Y, Ogawa M. Development of natural killer cells from lymphohematopoietic progenitors of murine fetal liver. Stem Cells. 1998; 16 Suppl 1:193-8.
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Ogawa M, Yonemura Y, Ku H. In vitro expansion of hematopoietic stem cells. Stem Cells. 1997; 15 Suppl 1:7-11; discussion 12.
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Ball TC, Hirayama F, Ogawa M. Modulation of early B lymphopoiesis by interleukin-3. Exp Hematol. 1996 Aug; 24(10):1225-31.
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Ku H, Yonemura Y, Kaushansky K, Ogawa M. Thrombopoietin, the ligand for the Mpl receptor, synergizes with steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice. Blood. 1996 Jun 01; 87(11):4544-51.
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Hirayama F, Ogawa M. Negative regulation of early T lymphopoiesis by interleukin-3 and interleukin-1 alpha. Blood. 1995 Dec 15; 86(12):4527-31.
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Tsuji K, Lyman SD, Sudo T, Clark SC, Ogawa M. Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. Blood. 1992 Jun 01; 79(11):2855-60.