Protein Interaction Domains and Motifs

"Protein Interaction Domains and Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Protein modules with conserved ligand-binding surfaces which mediate specific interaction functions in SIGNAL TRANSDUCTION PATHWAYS and the specific BINDING SITES of their cognate protein LIGANDS.

Descriptor ID	D054730
MeSH Number(s)	G02.111.570.820.709.275.750.500
Concept/Terms	Protein Interaction Domains and Motifs Protein Interaction Domains and Motifs Protein Interaction Motifs Protein Interaction Motifs Motif, Protein Interaction Motifs, Protein Interaction Protein Interaction Motif Binding Motifs, Protein Interaction Protein Interaction Binding Motifs Protein Interaction Domains Protein Interaction Domains Domain, Protein Interaction Domains, Protein Interaction Protein Interaction Domain Protein-Protein Interaction Domains Domain, Protein-Protein Interaction Domains, Protein-Protein Interaction Protein Protein Interaction Domains Protein-Protein Interaction Domain

Below are MeSH descriptors whose meaning is more general than "Protein Interaction Domains and Motifs".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.820]
Protein Conformation [G02.111.570.820.709]
Protein Structural Elements [G02.111.570.820.709.275]
Protein Domains [G02.111.570.820.709.275.750]
Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]

Below are MeSH descriptors whose meaning is related to "Protein Interaction Domains and Motifs".

Below are MeSH descriptors whose meaning is more specific than "Protein Interaction Domains and Motifs".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein Interaction Domains and Motifs" by people in this website by year, and whether "Protein Interaction Domains and Motifs" was a major or minor topic of these publications.

Bar chart showing 40 publications over 12 distinct years, with a maximum of 5 publications in 2013 and 2015 and 2016 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	0	2	2
2010	0	1	1
2011	0	3	3
2012	1	2	3
2013	2	3	5
2014	0	1	1
2015	1	4	5
2016	0	5	5
2017	0	4	4
2018	0	2	2
2019	1	4	5
2021	0	4	4

Below are the most recent publications written about "Protein Interaction Domains and Motifs" by people in Profiles.

Gao X, Qin S, Wu Y, Chu C, Jiang B, Johnson RH, Kuang D, Zhang J, Wang X, Mehta A, Tew KD, Leone GW, Yu XZ, Wang H. Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia. J Clin Invest. 2021 08 16; 131(16).

View in: PubMed
Bassenden AV, Dumalo L, Park J, Blanchet J, Maiti K, Arya DP, Berghuis AM. Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes. Sci Rep. 2021 06 02; 11(1):11614.

View in: PubMed
Tibble RW, Depaix A, Kowalska J, Jemielity J, Gross JD. Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation. Nat Chem Biol. 2021 05; 17(5):615-623.

View in: PubMed
Basak S, Sakia N, Dougherty L, Guo Z, Wu F, Mindlin F, Lary JW, Cole JL, Ding F, Bowen ME. Probing Interdomain Linkers and Protein Supertertiary Structure In Vitro and in Live Cells with Fluorescent Protein Resonance Energy Transfer. J Mol Biol. 2021 03 05; 433(5):166793.

View in: PubMed
Chidananda AH, Sharma AK, Khandelwal R, Sharma Y. Secretagogin Binding Prevents a-Synuclein Fibrillation. Biochemistry. 2019 11 19; 58(46):4585-4589.

View in: PubMed
Abelin JG, Harjanto D, Malloy M, Suri P, Colson T, Goulding SP, Creech AL, Serrano LR, Nasir G, Nasrullah Y, McGann CD, Velez D, Ting YS, Poran A, Rothenberg DA, Chhangawala S, Rubinsteyn A, Hammerbacher J, Gaynor RB, Fritsch EF, Greshock J, Oslund RC, Barthelme D, Addona TA, Arieta CM, Rooney MS. Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction. Immunity. 2019 10 15; 51(4):766-779.e17.

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Ahuja LG, Aoto PC, Kornev AP, Veglia G, Taylor SS. Dynamic allostery-based molecular workings of kinase:peptide complexes. Proc Natl Acad Sci U S A. 2019 07 23; 116(30):15052-15061.

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Chitrala KN, Nagarkatti M, Nagarkatti P, Yeguvapalli S. Analysis of the TP53 Deleterious Single Nucleotide Polymorphisms Impact on Estrogen Receptor Alpha-p53 Interaction: A Machine Learning Approach. Int J Mol Sci. 2019 Jun 18; 20(12).

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Jacobs D, Hoogerheide DP, Rovini A, Jiang Z, Lee JC, Rostovtseva TK, Bezrukov SM. Probing Membrane Association of a-Synuclein Domains with VDAC Nanopore Reveals Unexpected Binding Pattern. Sci Rep. 2019 03 14; 9(1):4580.

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Zhang J, Chen M, Zhu Y, Dai X, Dang F, Ren J, Ren S, Shulga YV, Beca F, Gan W, Wu F, Lin YM, Zhou X, DeCaprio JA, Beck AH, Lu KP, Huang J, Zhao C, Sun Y, Gao X, Pandolfi PP, Wei W. SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression. Dev Cell. 2019 02 11; 48(3):329-344.e5.

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